20 articles
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
Researchers developed a method to rejuvenate aging stem cells, extending their lifespan beyond 100 days while preserving function.
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging — from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
Tumor-infiltrating lymphocyte therapies are emerging as a powerful cancer treatment. Here's what the science says and why it matters for longevity.
Dive deep into partial reprogramming, niche remodeling, senolytics, and cutting-edge clinical therapies — the molecular toolkit for reversing stem cell aging.
Scientists review breakthrough methods for transferring healthy mitochondria into damaged cells to restore cellular energy and combat aging.
Intellia's in vivo CRISPR treatment edits genes directly inside living patients and just cleared a Phase 3 trial — a world first.
New research reveals how LMNA gene mutations cause premature aging in heart cells by shortening protective telomeres.
PARP inhibitors have transformed cancer treatment, but resistance and toxicity are emerging as serious limits to their long-term effectiveness.
New research reveals stem cells from urine contain telomerase activity that could combat aging by maintaining telomeres and rejuvenating tissues.
A redesigned CRISPR system targets the chromosomal root cause of Down syndrome, opening new doors for genetic disease intervention.
Activating three Yamanaka factors — OCT4, SOX2, and KLF4 — appears to reverse epigenetic aging in human eye cells, marking a milestone in rejuvenation medicine.
A rigorous mechanistic deep-dive into the molecular logic of partial reprogramming — from chromatin dynamics and epigenetic clock reversal to in vivo delivery strategies, oncogenic risks, and the path to clinical translation.
Breakthrough review reveals how modern diabetes treatments protect multiple organs and may extend healthy lifespan through novel mechanisms.
Discover how four tiny proteins can turn back the clock on aging cells — and what this means for the future of medicine and longevity.
A new class of drugs called proximity degraders can destroy disease-causing proteins once considered untreatable. Here's what's coming next.
New minimally evolved base editors show enhanced precision and efficiency, potentially advancing genetic therapies for age-related diseases.
Dihydrotestosterone treatment restored heart function in aging mice by activating DNA repair mechanisms and reducing inflammation.
Prime editing successfully corrected genetic mutations causing severe skin blistering, with implications for skin aging and regeneration.
New technique combines your own cells with light therapy to supercharge mitochondria for dramatic skin regeneration and wound healing.
