Dietary Nucleotides Show Promise as Anti-Aging Supplements in 4-Month Clinical Trial
Chinese researchers tested nucleotide supplements against aging markers in 122 participants over 4 months with promising early results.
20 articles
Chinese researchers tested nucleotide supplements against aging markers in 122 participants over 4 months with promising early results.
A mechanistic deep dive into hormone replacement therapy evidence, growth hormone secretagogues, DHEA pharmacology, and cutting-edge endocrine reprogramming strategies โ with clinical trial data and actionable protocols.
Two popular longevity drugs show evidence of interfering with the body's response to exercise โ a critical tradeoff for active users.
German researchers tested whether 4g daily taurine could slow aging processes in adults 55-75 over 6 months of supplementation.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
Explore how resveratrol activates sirtuins, the 'longevity proteins' that may slow aging and extend healthspan through cellular repair mechanisms.
A quercetin, NR, urolithin A, and alpha-lipoic acid combination boosted remaining lifespan in aged mice by 33%, even on a Western diet.
A double-blind RCT finds daily spermidine supplementation reverses immune senescence markers and boosts vaccine antibody responses in adults over 65.

A practicing physician rates 10 trending health interventions based on actual longevity benefits, revealing surprising winners and losers.
DuoStim lets women with poor ovarian reserve collect more eggs in one cycle, potentially cutting time to a successful pregnancy.
New research reveals how polyamine molecules regulate cellular aging and may offer promising anti-aging interventions.
New study reveals reduced forms of NAD precursors trigger broader cellular changes and more potent longevity benefits than current supplements.
Single-nucleus RNA sequencing reveals TRT partially reverses fibrotic and inflammatory muscle changes in hypogonadal Klinefelter men.
Scientists discover how deleting STIM1 protein in regulatory T-cells prevents lung fibrosis and cardiovascular complications.
Hypothermic machine perfusion reduces liver damage during transplant by activating cellular pathways that remove damaged mitochondria.
Dietary compounds like resveratrol and quercetin enhance immune cell function and combat age-related immune decline.
New trial explores whether short-term testosterone treatment creates lasting muscle benefits in older men through epigenetic memory.
New research reveals how the mitochondrial protein Lonp1 protects brain cells from aging-related damage and cognitive decline.
Review reveals how compounds in berries, tea, and spices may preserve muscle mass in aging through DNA modifications.
12-week omega-3 trial tested whether fish oil could reverse accelerated immune system aging in HIV-infected older adults.