New Drug Discovery Methods Could Accelerate Longevity Therapeutics
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
20 articles
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
New review reveals how senescent cells both prevent and promote cancer, opening therapeutic opportunities.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
Aging disrupts gut microbiota and mTOR signaling, crippling vaccine responses โ but targeted interventions may reverse this.
A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
A landmark review maps the three pillars of modern lineage tracing and how they're reshaping our understanding of cell fate decisions.
Scientists propose space environments as unique models for studying accelerated aging mechanisms and potential interventions.
New review reveals how advanced genomics tools are revolutionizing cancer diagnosis and therapy development.
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Age-related shifts in intestinal T cell populations may silently erode gut barrier function, accelerating the chronic inflammation that drives aging diseases.
A landmark review reveals how diet, gut bacteria, and their metabolites determine the success of immune checkpoint blockade cancer therapy.
A new framework proposes organ-specific biological clocks using multi-omics data to better predict disease onset and aging trajectories.
Continuous glucose monitors are popular in biohacking circles, but direct evidence linking CGM use to extended lifespan remains thin.
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.