Brain Cancer Trial Uses Patient's Own Tumor Cells to Train Immune System
Innovative immunotherapy approach converts patient tumor cells into personalized vaccines to fight aggressive brain cancer.
20 articles
Innovative immunotherapy approach converts patient tumor cells into personalized vaccines to fight aggressive brain cancer.
New review reveals why fecal microbiota transplants sometimes help—and sometimes hurt—immune checkpoint inhibitor cancer treatments.
Revolutionary CRISPR technique bypasses lab manufacturing by programming immune cells to fight cancer directly in the body.
New research reveals how gut microbiome restoration could treat inflammatory bowel disease and boost cancer treatments.
Redesigned immunotherapy injected into one tumor triggered complete cancer remission in 2 of 12 patients, with untreated tumors also disappearing.
Scientists expand granulocyte-monocyte progenitors into a scalable CAR platform that infiltrates tumors and fights leukemia and solid cancers.
Harvard researchers demonstrate that activated macrophages can both trigger immune responses and infiltrate tumors directly.
Revolutionary in vivo CRISPR technique creates more effective cancer-fighting immune cells without lab manipulation.
Engineered immune cells target harmful macrophages in tumors, transforming the cancer environment to boost natural anti-tumor immunity.
Comprehensive comparison of Stereo-seq, Visium HD, CosMx, and Xenium platforms reveals key performance differences for cancer research applications.
Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.
Small trial tests novel three-drug approach combining immune checkpoint inhibitor, vaccine, and inflammation blocker for metastatic cancers.
Novel treatment triggers ferroptosis in cancer cells while activating immune responses that further enhance cancer cell death.
A phase 1 trial shows Temferon — a gene-engineered stem cell therapy — safely delivers interferon-α into glioblastoma tumors with no dose-limiting toxicities.
Breakthrough therapy converts tumor cells into antigen-presenting cells that train immune system to destroy cancer.
Synthetic super-enhancers hijack glioblastoma's own regulatory circuits to trigger precise, tumor-only cell death and durable immune memory.
Scientists develop antibodies that stabilize drug-modified KRAS mutations, enabling targeted immune responses across different genetic backgrounds.
New review reveals how targeting mitochondria in cancer cells could overcome immunotherapy resistance and enhance anti-tumor responses.
Blocking CysLTR1 reprograms immunosuppressive neutrophils and reverses resistance to anti-PD1 checkpoint therapy in mice.
New research reveals how tumors sabotage T cell metabolism by transferring dysfunctional mitochondria, offering fresh immunotherapy targets.