Longevity & Aging
Pig-to-Human Organ Transplants Edge Closer to Clinical Reality
After 120 years of failed attempts, genetic engineering is finally making xenotransplantation viable. Here's where the science stands.
Research Paper
Jun 24, 2026 0
Results for "Xenotransplantation"
20 articles
Longevity & Aging
AI and Xenotransplantation Could Revolutionize Organ Transplants
New review explores how artificial intelligence, pig organs, and regenerative medicine may solve the organ shortage crisis.
Research Paper
Apr 6, 2026 0
Regenerative Medicine
Stanford Team Cracks the Immune Barrier Blocking Human Organ Growth in Animals
Researchers identify how host macrophages destroy foreign cells in embryos — and three strategies to stop it, boosting organ-growing chimeras.
Research Paper
Jun 8, 2026 0
Regenerative Medicine
How Pig Organs, Bioprinted Tissue and Stem Cells Could End Transplant Waitlists
Xenotransplantation, 3D bioprinting, and stem cell therapies are converging to solve the global organ shortage crisis.
Press Release
May 28, 2026 0
Longevity & Aging
Donor Stem Cell Infusions Fail to Induce Kidney Transplant Tolerance and May Sensitize
A dual human-primate trial finds donor MSC infusions are safe but do not establish chimerism or tolerance, and may trigger rejection-causing antibodies.
Research Paper
Jun 14, 2026 0
Heart Health
New Strategy Targets Lymph Node Pathways to Prevent Heart Transplant Rejection
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Research Paper
May 19, 2026 0
Metabolic Health
New Local Immune Engineering Approach Could Transform Diabetes Islet Transplants
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Research Paper
Mar 28, 2026 0
Regenerative Medicine
Scientists Combine Cellular Reprogramming with Ex Vivo Organ Perfusion for Transplants
Researchers propose using partial reprogramming to rejuvenate donor organs outside the body before transplantation.
Research Paper
Apr 3, 2026 0
Regenerative Medicine
New Ferroptosis Inhibitors Dramatically Improve Liver and Lung Transplant Outcomes
A novel class of ferroptosis inhibitors protects donor organs from ischemia-reperfusion injury, potentially saving thousands of transplant patients annually.
Research Paper
May 11, 2026 0
Regenerative Medicine
Bioengineered Esophageal Grafts Show Functional Integration in Porcine Model
Scientists combine tissue engineering and transplantation to build a working esophageal graft, marking a step toward lab-grown organ replacements.
Research Paper
Jun 7, 2026 0
Metabolic Health
New Immune Engineering Approach Shows Promise for Diabetes Islet Transplants
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
Research Paper
Mar 28, 2026 0
Longevity & Aging
Immunosuppressive Drugs May Alter Extracellular Vesicles in Organ Transplants
Review explores how transplant medications affect cellular communication particles that trigger immune rejection responses.
Research Paper
Apr 18, 2026 0
Regenerative Medicine
New Crystal Drug Protects Transplanted Cells Without Immune Suppression for One Year
Breakthrough crystal technology enables transplanted insulin-producing cells to survive and function for a full year without traditional immunosuppression.
Research Paper
Mar 29, 2026 0
Longevity & Aging
Fecal Transplants May Cause Unintended Metabolic and Immune Effects
Study reveals regional microbiome mismatches from FMT can lead to persistent off-target effects on metabolism and immunity.
Research Paper
Apr 9, 2026 0
Regenerative Medicine
Stem Cell-Derived Hepatocytes Could Replace Liver Transplants
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Review
May 9, 2026 0
Longevity & Aging
Cancer Risk Soars After Organ Transplants Due to Immunosuppression
Transplant recipients face dramatically higher cancer rates, especially skin and virus-linked tumors, requiring intensive surveillance.
Research Paper
Apr 20, 2026 0
Regenerative Medicine
New Biomarker Predicts Success of Diabetes Islet Transplants with 90% Accuracy
Scientists discover NKX6.1 gene expression can predict which pancreatic islet transplants will succeed in treating type 1 diabetes.
Research Paper
Mar 28, 2026 0
Regenerative Medicine
Scientists Successfully Grow and Transplant Functional Esophagus in Large Animals
Breakthrough tissue engineering creates working esophageal segments that support normal feeding and growth in minipigs.
Research Paper
Mar 28, 2026 1
Longevity & Aging
CAR T-Cell Therapy Clears Immune Barriers to Enable Kidney Transplants in Near-Impossible Cases
A novel dual CAR T-cell approach eliminated blocking antibodies in highly sensitized patients, enabling kidney transplants previously considered impossible.
Press Release
Jun 4, 2026 0
Regenerative Medicine
Zinc Inhibition Helps Lab-Grown Pancreatic Cells Survive Transplantation
Blocking zinc transport in stem cell-derived pancreatic islets improves their survival and function after transplantation for diabetes treatment.
Research Paper
Apr 8, 2026 0
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