20 articles
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Scientists discover how to enhance cancer immunotherapy by converting tumor-supporting immune cells into tumor-fighting ones.
Major cholesterol-lowering drug alirocumab didn't reduce artery plaque buildup in heart transplant patients, despite cutting LDL by 57%.
First-in-human study demonstrates successful transcatheter replacement of mechanical heart valves without open surgery.
Revolutionary nanobody drug targets two proteins simultaneously, achieving complete tumor elimination in preclinical studies.
Novel liposome therapy delivers miR-10a to atherosclerotic plaques, reprogramming inflammatory macrophages and reducing disease progression in mice.
An AI-powered ECG algorithm flagged hidden structural heart disease, setting a patient on the path to a successful heart transplant.
A 330-patient multicenter RCT tests whether thymosin α1 can curb immune dysregulation and organ dysfunction after acute type A aortic dissection repair.
Researchers created synthetic immune receptors that boost macrophages' ability to clear cellular debris, reducing inflammation in liver and heart disease.
CAR-M2 therapy successfully reversed kidney scarring in lab studies by eliminating harmful endothelial cells and promoting healing.
New genetic approach could revolutionize how we develop heart medications, potentially saving billions in failed drug trials.
Revolutionary gene-editing technology CRISPR becomes available outside the US, offering new hope for treating genetic diseases worldwide.
Natural isoflavone prevents cardiac enlargement through novel mitochondrial protection pathway, offering new therapeutic approach.
Scientists discover how damaged heart cells transform into new blood vessels, potentially revolutionizing heart failure treatment.
A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.
Small trial tests safety of injecting patients' own cardiac stem cells to regrow dead heart tissue and restore function.
Clinical trial tested whether bone marrow stem cells could improve heart function beyond standard bypass surgery alone.
Researchers tested injecting cardiac stem cells directly into heart arteries after heart attacks to promote healing and regeneration.
UC San Diego scientists developed an injectable hydrogel that travels the bloodstream to reduce inflammation and regenerate damaged heart tissue.
Scientists discover targeting two cellular pathways simultaneously could overcome treatment resistance in neuroendocrine tumors.
