20 articles
Researchers identify how host macrophages destroy foreign cells in embryos — and three strategies to stop it, boosting organ-growing chimeras.
Xenotransplantation, 3D bioprinting, and stem cell therapies are converging to solve the global organ shortage crisis.
Researchers propose using partial reprogramming to rejuvenate donor organs outside the body before transplantation.
A novel class of ferroptosis inhibitors protects donor organs from ischemia-reperfusion injury, potentially saving thousands of transplant patients annually.
Scientists combine tissue engineering and transplantation to build a working esophageal graft, marking a step toward lab-grown organ replacements.
Breakthrough crystal technology enables transplanted insulin-producing cells to survive and function for a full year without traditional immunosuppression.
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Scientists discover NKX6.1 gene expression can predict which pancreatic islet transplants will succeed in treating type 1 diabetes.
Breakthrough tissue engineering creates working esophageal segments that support normal feeding and growth in minipigs.
Blocking zinc transport in stem cell-derived pancreatic islets improves their survival and function after transplantation for diabetes treatment.
A landmark clinical trial transplanted iPSC-derived dopamine neurons into Parkinson's patients using only tacrolimus — with no significant immune rejection.
Packaging mitochondria in erythrocyte-derived membranes dramatically improves delivery efficiency, pushing this experimental therapy closer to clinical reality.
A Nature Medicine short-form item by K. O'Leary whose title points to digital twin technology applied to donor lungs; only title-level metadata was available for review.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
Scientists review breakthrough methods for transferring healthy mitochondria into damaged cells to restore cellular energy and combat aging.
Global survey reveals robotic surgery is driving rapid adoption of minimally invasive donor liver surgery, with one-third of procedures now performed this way.
New review explores how lab-grown organ models are revolutionizing personalized medicine and drug development.
A UC Berkeley spinout is developing a one-time gene therapy using transposons to sustain GLP-1 activity — potentially replacing daily weight loss drugs.
New research reveals tissue-specific barriers to AAV9 gene therapy effectiveness, particularly in liver cells of primates.
Adding a vascular network to stem cell-derived islet organoids dramatically improves beta-cell calcium signaling, insulin secretion, and diabetes reversal in mice.
