Stem Cell-Derived Hepatocytes Could Replace Liver Transplants
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
20 articles
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Bacteriophages transferred during FMT may drive horizontal gene transfer, altering microbial function and antibiotic resistance in ways science has largely ignored.
New review explores how 3D organoids and bioengineered niches are revolutionizing tumor research and treatment development.
Virtual patient replicas built from multimodal data may slash trial costs, generate synthetic control arms, and predict treatment response in IBD.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
A Dana-Farber review maps the path for personalized cancer vaccines — pinpointing which tumors, timing, and combination strategies will matter most.
A new perspective in Nature Cancer outlines how genetically engineered bacteria can target and destroy tumors from within.
New review reveals how advanced genomics tools are revolutionizing cancer diagnosis and therapy development.
A landmark review reveals how diet, gut bacteria, and their metabolites determine the success of immune checkpoint blockade cancer therapy.
A new review maps the structural and functional changes that help the bowel compensate after resection, and highlights where knowledge gaps remain.
A new review maps how tirzepatide's dual GIP/GLP-1 action reshapes metabolism across the pancreas, liver, gut, heart, kidneys, and brain.
A new review reveals how epithelial-to-mesenchymal transition fuels tumor invasion, immune evasion, and drug resistance through dynamic, reversible states.
Machine learning and whole-genome sequencing may finally give doctors the tools to predict bacterial resistance before treatment fails.
A new review traces how aging science evolved from single-cause theories to partial reprogramming with Yamanaka factors as a lifespan-extending strategy.
The British Society of Gastroenterology's expert panel takes stock of 10 years of microbiome advances and where the field is headed.
A new review reframes how myeloid cells fuel or fight tumors, pointing to plasticity — not just cell diversity — as the core therapeutic target.
New computational advances help identify which tumor peptides trigger immune responses, potentially revolutionizing personalized cancer therapy.
A new review reveals how senescent healthy cells within tumors quietly drive cancer progression and therapy resistance.
A landmark review maps the three pillars of modern lineage tracing and how they're reshaping our understanding of cell fate decisions.
A new framework reveals how lactate and β-hydroxybutyrate team up across organs to regulate metabolism, mitochondria, and disease.