The Complete Guide to Cellular Aging Models and How to Reverse Them
A comprehensive review maps every major in vitro aging modelβfrom Hayflick's fibroblasts to iPSCsβand the interventions that reverse cellular aging.
15 articles
A comprehensive review maps every major in vitro aging modelβfrom Hayflick's fibroblasts to iPSCsβand the interventions that reverse cellular aging.
A 2025 narrative review maps how regenerative medicine, epigenetics, AI, and microbiome science are transforming cosmetic dermatology.
Scientists demonstrate how brief activation of cellular reprogramming factors can rejuvenate aged organs and restore regenerative capacity safely.
Revolutionary approach using Yamanaka factors shows promise for restoring youthful function to aging retinal cells and treating blindness.
Placental stem cell vesicles containing microRNAs reactivate aging neural cells through OSKM transcription factors.
New study reveals why promising chemical cocktails for cellular rejuvenation fail in living mice - dangerous fat accumulation.
Researchers propose using partial reprogramming to rejuvenate donor organs outside the body before transplantation.
Researchers identify methods to induce powerful regenerative cell clusters in mammals using temporary pluripotency factors.
Scientists discover how reprogramming factors rejuvenate eye cells and restore vision by activating a protective enzyme that clears toxic lipids.
Japanese researchers develop minimally invasive method to transform T cells into glutamatergic neurons using just 5 factors.
New research reveals how cellular identity loss accelerates aging and disease, but Yamanaka factors can reverse this process.
Researchers developed a method to artificially age stem cells, creating better models for studying neurodegeneration and other age-related conditions.
New small-molecule approach offers safer alternative to genetic reprogramming for turning back the cellular clock.
New research reveals why stem cells from Alzheimer's patients retain disease signatures that affect brain development.
The father of induced pluripotent stem cells discusses regenerative medicine milestones and future therapeutic potential.