Engineered Mammary Organoids Act as Living Drug Depots to Fight Breast Cancer Recurrence
Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.
310 articles in this topic
Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.
Japan's April 2026 revised guidelines now govern stem cell-based embryo models, marking a global regulatory milestone.
A biodegradable microneedle stent achieves sutureless intestinal anastomosis while releasing anti-inflammatory drugs triggered by local inflammation.
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.
A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.
Researchers improve ADAR-based RNA editing precision using guide RNAs modeled on highly edited natural substrates.
Scientists uncover how corals repeatedly evolved a specialized organelle to house algal partners — by hijacking their own lysosomal machinery.
Psychological stress impairs hematopoietic stem cells by suppressing brain regions, depleting gut microbiome-derived spermidine, and triggering ferroptosis.
A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.
Dasatinib + quercetin clears senescent kidney cells, restores anti-aging protein Klotho, and reverses transcriptional aging across multiple renal cell types.
Adding a vascular network to stem cell-derived islet organoids dramatically improves beta-cell calcium signaling, insulin secretion, and diabetes reversal in mice.