Longevity & AgingDog Aging Project Builds Landmark Multi-Omic Cohort to Decode Aging Biology
The Dog Aging Project (DAP) launched a precision cohort of ~1,000 companion dogs to study aging mechanisms through longitudinal multi-omic profiling. Stratified by life stage, sex, size, and geography, 976 dog-owner pairs were recruited via private veterinary clinics across the US. Biospecimens—blood, urine, feces, and hair—were collected and processed for complete blood count, chemistry panels, flow cytometry immunophenotyping, metabolomics, fecal microbiome sequencing, and epigenomic profiling. Data management was handled through a custom REDCap platform. The cohort is already in its second and third annual collection waves, building a rich longitudinal dataset. All data are openly accessible to researchers worldwide, positioning dogs as a powerful translational model for human geroscience.
