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Polyphenols Show Broad Antiviral Activity Against Drug-Resistant Viruses

This comprehensive review examines how polyphenols—plant compounds found in tea, wine, and berries—demonstrate powerful antiviral properties against drug-resistant viruses. Researchers analyzed over 8,000 known polyphenols, focusing on six major classes including flavonoids and tannins. Key compounds like epigallocatechin-3-gallate (EGCG) from green tea and resveratrol from grapes showed effectiveness against enveloped viruses including herpes, hepatitis B, influenza, and coronaviruses. The polyphenols work by interfering with virtually every stage of viral infection—from initial attachment to viral release—making them promising alternatives or supplements to conventional antivirals.

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