Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
794 articles
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
A completed Columbia University trial compares Family Nurture Intervention in group settings to standard programs for children ages 2–4.5.
Buck Institute finds the longevity-linked APOE2 variant shields neurons from DNA damage and cellular senescence, explaining its Alzheimer's protection.
Wellcovorin becomes the first approved treatment for cerebral folate deficiency tied to FOLR1 gene variants, offering hope for a rare neurological condition.
Resting-state EEG slow waves predict amyloid buildup and neurodegeneration in cognitively normal older adults, offering a non-invasive early warning tool.
Genetic variants in the water channel gene AQP4 directly affect brain volume and cognition — and interact with sleep to accelerate Alzheimer's progression.
New research shows caffeine selectively restores a brain circuit for social memory damaged by sleep loss, without overstimulating healthy neurons.
New research in Cell maps the fronto-insular circuits behind accelerated TMS, potentially transforming rapid depression treatment.
New spatiotemporal mapping of the human meninges exposes how immune cells and brain barriers co-develop from 6–23 gestational weeks.
A new genetic tracing system reveals the brain's waste-clearance routes are compartmentalized, rapid in some areas, and disrupted differently by inflammation vs. amyloid.
A neuron-specific proteasome system governs tau pathology, with APOE4 carriers showing heightened vulnerability as this system declines with age.
A new Nature Neuroscience study reveals an unexpected molecular mechanism that initiates tau aggregation, the hallmark of Alzheimer's disease.
