Brain Health

Lab-Grown Amygdala Organoids Reveal How Stress Hormones Rewire the Brain

Scientists built human amygdala-like brain organoids that model stress circuitry, uncovering a novel cortisol-driven mechanism tied to primate-specific gene regulation.

Research Paper

Duke Study Tests Blood Biomarker to Catch Alzheimer's Before Symptoms Strike

Researchers at Duke University tested a blood-based biomarker to stratify Alzheimer's patients from healthy adults, aiming to enable earlier detection.

Clinical Trial

When Wellness Becomes the Problem: The Psychology Behind Optimization Culture

Sarah Ann Macklin and Simon Hill explore how relentless health optimization creates anxiety, perfectionism, and a broken relationship with your own body.

Podcast

The Neuroscience of Grief and How to Heal Faster According to Brain Science

Huberman explains how the brain remaps lost relationships and which science-backed tools accelerate adaptive grieving.

Podcast

Silencing SMARCAD1 Gene Reduces Tau Protein and Rescues Brain Cells in Alzheimer's Models

A chromatin-remodeling gene called SMARCAD1 controls tau levels — and switching it off could be a new therapeutic target for Alzheimer's.

Research Paper

Hidden Proteasome Subtype Clears Parkinson's Toxic Protein and Resists Cellular Blockade

A newly identified proteasome activator, PA200, clears toxic alpha-synuclein aggregates and maintains function even when standard protein-disposal systems fail.

Neuroendocrine Longevity: Advanced Mechanisms of Hypothalamic Aging and Therapeutic Targeting

A deep mechanistic exploration of how hypothalamic IKKβ/NF-κB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging — plus cutting-edge therapeutic strategies.

TutorialAdvanced

Popular Anti-Aging Drug Combo Dasatinib+Quercetin Causes Brain Damage in Mice

New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.

Press Release

Arthritis Drug Eases Treatment-Resistant Depression by Calming Inflammation

A small trial found tocilizumab, an anti-inflammatory drug, cut depression remission rates better than SSRIs by targeting IL-6, not brain chemistry.

Press Release

Dasatinib and Quercetin Reach the Brain in Early Alzheimer's Patients

A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.

Clinical Trial

Prescription vs OTC Hearing Aids: What Adults With Mild to Moderate Hearing Loss Need to Know

A JAMA Insights review breaks down how hearing aids work, their limits, and whether OTC devices stack up against prescription options.

Research Paper