Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
794 articles
A landmark review reframes astrocytes as multilayered processing units that regulate synapses, circuits, and brain function at multiple spatial scales.
Go beneath the surface to explore how NF-κB signaling, IKKβ activation, and hypothalamic stem cell decline drive whole-body aging — and which interventions can slow the process.
A completed RCT tests whether trained non-clinicians can guide self-help CBT for generalized anxiety disorder in seniors.
Researchers respond to critiques of their trial showing positive airway pressure therapy may improve cognitive outcomes in Parkinson's disease.
New mouse study reveals why women face higher Alzheimer's risk — local brain estrogen deficiency triggers age-specific memory loss and ECM remodeling.
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
Deep inside your brain sits a tiny region that acts like a master control center for aging. Discover how the hypothalamus influences your lifespan — and what you can do to keep it young.
New NIH research reveals the brain-cell signaling mechanism behind GLP-1 drug plateaus and a potential way to extend their effects.
New compounds targeting the cPLA2 enzyme may reduce Alzheimer's-linked brain inflammation, especially in high-risk APOE4 gene carriers.
A Phase 4 real-world study comparing extended-release methylphenidate formulations for ADHD was terminated before yielding conclusions.
New research reveals eye fixation duration is driven by memory encoding demands, not visual processing difficulty — reshaping how we understand attention.
Duke researchers restored healthy mitochondria to damaged nerve cells, cutting pain-related behaviors by 50% in mice with nerve pain.
