Newly Discovered Axonic Spines Rewire How Neurons Fire Action Potentials
A surprising structural feature on axon initial segments lets excitatory synapses jump-start neuron firing and redirect brain circuit information flow.
Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
794 articles
A surprising structural feature on axon initial segments lets excitatory synapses jump-start neuron firing and redirect brain circuit information flow.
Norwegian researchers say short bursts of high-intensity effort just 4.5 minutes daily dramatically improve cardiovascular fitness and lifespan.
New research reveals that brain cells active after workouts—not just during—are key to building endurance over time.
A new tool that boosts mitochondrial activity in neurons restored memory in dementia mice, suggesting energy failure drives Alzheimer's symptoms.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
Transdermal alcohol monitors paired with machine learning can now detect drinking events with over 90% accuracy — a leap beyond flawed self-reports.
People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.
Researchers matched fMRI patterns across mouse models and 1,976 humans to find autism splits into hypo- and hyperconnectivity subtypes with distinct biology.
New fMRI research from UNC Chapel Hill uncovers distinct neurological subtypes within ASD, potentially reshaping diagnosis and treatment.
Cannabis use is surging among adults over 65, but Stanford Medicine specialists say today's potent marijuana carries serious, underestimated health risks.
Applied Cognition tests a wearable device that tracks glymphatic function overnight, comparing it to MRI, EEG, and blood biomarkers.
A Phase 1/2 trial tests whether dexmedetomidine can enhance the brain's glymphatic system to clear amyloid and tau during sleep.