Research Topic

Brain Health

Cognitive performance, neuroplasticity, dementia prevention, and brain aging research

794 articles

AQP4 Gene Variants Shape Parkinson's Brain Waste Clearance and Motor Decline
Brain Health

AQP4 Gene Variants Shape Parkinson's Brain Waste Clearance and Motor Decline

Specific AQP4 genetic variants alter glymphatic drainage efficiency, directly influencing motor symptom severity and progression in early Parkinson's disease.

Research Paper
May 16, 2026 0
Aging Brain Builds PNN Armor in Hippocampus While Striatum Stays Inflamed
Brain Health

Aging Brain Builds PNN Armor in Hippocampus While Striatum Stays Inflamed

New mouse study reveals aging causes region-specific neuroinflammation and perineuronal net accumulation linked to memory decline.

Research Paper
May 16, 2026 0
Treating Hearing Loss May Slow Cognitive Decline in Older Adults
Brain Health

Treating Hearing Loss May Slow Cognitive Decline in Older Adults

A landmark RCT tests whether hearing aids can protect brain health in 977 older adults over 3 years.

Clinical Trial
May 16, 2026 0
APOE2 and APOE4 Drive Alzheimer's Risk Through Opposite Protein Pathways
Brain Health

APOE2 and APOE4 Drive Alzheimer's Risk Through Opposite Protein Pathways

A landmark multicohort proteomics study reveals how APOE2 and APOE4 shape Alzheimer's risk through entirely distinct molecular mechanisms.

Research Paper
May 16, 2026 0
Green Tea Extract Plus Lifestyle Changes Tested Against Cognitive Decline in High-Risk Adults
Brain Health

Green Tea Extract Plus Lifestyle Changes Tested Against Cognitive Decline in High-Risk Adults

A completed trial tests EGCG combined with diet, exercise, and cognitive training to slow decline in ApoE4 carriers with early warning signs.

Clinical Trial
May 15, 2026 0
Your Brain's Internal State Shapes What You See Before You See It
Brain Health

Your Brain's Internal State Shapes What You See Before You See It

New research shows single V1 neurons in the visual cortex track internal arousal states, directly predicting perception and reaction speed.

Research Paper
May 15, 2026 0
Cerebellum Uses Synchronized Neural Firing to Gate Motor Learning Circuits
Brain Health

Cerebellum Uses Synchronized Neural Firing to Gate Motor Learning Circuits

New research reveals how the brain selectively triggers learning only during meaningful errors — not random neural noise.

Research Paper
May 15, 2026 0
ALS Study Maps How Immune Cells Invade the Spine and Drive Motor Neuron Loss
Brain Health

ALS Study Maps How Immune Cells Invade the Spine and Drive Motor Neuron Loss

A landmark Nature Neuroscience study reveals how peripheral immune cells infiltrate the spinal cord in ALS, pointing to targeted immunotherapy.

Research Paper
May 15, 2026 0
Declining ULK1 Protein Links Autophagy Failure to Alzheimer's Progression
Brain Health

Declining ULK1 Protein Links Autophagy Failure to Alzheimer's Progression

A master autophagy regulator drops with age and in AD patients — restoring it in mice clears amyloid, reduces tau, and rescues cognition.

Research Paper
May 15, 2026 0
How to Control Aggression Using Neuroscience and Simple Daily Tools
Brain Health

How to Control Aggression Using Neuroscience and Simple Daily Tools

Huberman breaks down the brain circuits behind aggression and shares evidence-based tools — sunlight, sauna, ashwagandha — to dial it down.

Podcast
May 15, 2026 0
New Psychedelic-Like Compounds Treat Depression Without Causing Hallucinations
Brain Health

New Psychedelic-Like Compounds Treat Depression Without Causing Hallucinations

UC Davis scientists created novel brain-healing molecules that activate key serotonin receptors tied to neuroplasticity — without triggering hallucinations.

Press Release
May 14, 2026 0
Junk DNA Drives Human Brain Development via Ancient Genetic Parasites
Brain Health

Junk DNA Drives Human Brain Development via Ancient Genetic Parasites

LINE-1 retrotransposons act as alternative gene promoters in human stem cells, and silencing them shrinks cerebral organoids.

Research Paper
May 14, 2026 0
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