Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
794 articles
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
A bibliometric analysis of 595 papers maps how glymphatic-Alzheimer's research has grown exponentially, pinpointing AQP4, sleep, and DTI-ALPS imaging as the hottest frontiers.
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation — and restoring blood flow with levosimendan reverses it.
HIE disrupts the glymphatic system in neonatal brains, impairing waste clearance and development with lasting consequences.
A comprehensive review details how NMOSD, MOGAD, and other rare CNS disorders are frequently mistaken for MS — and how to tell them apart.
A completed RCT tests whether treating insomnia with CBT-I can improve cognition and slow amyloid buildup in adults aged 60–85.
Boosting BNIP3 in muscle tissue extends fly lifespan and shields the brain from age-related degeneration via a muscle-brain signaling axis.
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
A major review reveals how the glymphatic system's failure drives neurodegeneration and brain tumor resistance — and how to fix it.
Blocking brain lymphatic drainage triggers age-dependent compensatory responses — young rats adapt, middle-aged rats largely cannot, with proteomic signs of neurodegeneration in both.
New mouse study reveals how the brain's waste-clearance system modulates toxic protein buildup linked to Parkinson's disease.
PET-MRI study of 54 cSVD patients links microglial activation to enlarged white matter perivascular spaces, not BBB leakage.
