Liver Cancer Cells Release Compound That Blocks Immune Response to Treatment
New research reveals how hepatoma cells evade immunotherapy by secreting N1-acetylspermidine to suppress immune function.
Oncology, cancer prevention, tumor biology, and immunotherapy relevant to longevity
316 articles
New research reveals how hepatoma cells evade immunotherapy by secreting N1-acetylspermidine to suppress immune function.
Combining two targeted drugs plus dietary changes shows superior cancer-fighting potential in lab studies of breast and endometrial cancers.
Research identifies genetic and environmental factors that may help predict who develops pancreatic neuroendocrine tumors and their outcomes.
New ColonTrack model identifies early-stage colorectal cancer with 94% accuracy using three proteins from blood-based extracellular vesicles.
New research reveals cancer cells can escape therapy-induced senescence, creating a reversible drug resistance mechanism that may contribute to tumor relapse.
BCG therapy for bladder cancer travels to bone marrow, reprogramming stem cells to produce enhanced immune cells that fight tumors throughout the body.
Study identifies senescent EGR1+ B cells that sabotage immunotherapy in esophageal cancer, with fisetin showing promise as a therapeutic enhancer.
New nanotechnology selectively destroys cancer cell mitochondria, making tumors more vulnerable to T cell attacks across multiple cancer types.
New research reveals how LARP4 protein causes T cells to malfunction in tumors by disrupting cellular energy production.
Researchers integrated brain protein and gene data to identify EGFR, SCFD1, and GMPPB as promising new targets for treating deadly brain cancer.
Multi-omics analysis reveals SASH1 protein loss predicts worse outcomes in head and neck cancer patients and guides targeted therapy selection.
Researchers discover how cancer cells use lysosomes to resist RNA polymerase inhibitors and develop combination strategies to overcome this resistance.