Oncology, cancer prevention, tumor biology, and immunotherapy relevant to longevity
516 articles
Researchers identify four LSC subtypes that predict venetoclax resistance and reveal matched subtype-specific therapies for AML patients.
A new editorial in Gut explores how AI-powered radiomic analysis could identify occult pancreatic cancer missed by standard imaging.
The landmark NordICC trial's 13-year data shows one colonoscopy meaningfully reduces cancer incidence but doesn't significantly lower mortality.
Researchers discover a BBB-like vascular shield in small cell lung cancer that blocks immune cells — and find a drug combo to overcome it.
Long-elusive cancer-driving proteins are yielding to innovative drug strategies, opening new frontiers in oncology treatment.
A Nature study reveals neurons physically transfer mitochondria to breast cancer cells via tunneling nanotubes, boosting metastatic potential.
A high-MAPK, low-WNT tumor cell state drives CRC metastasis, and blocking mutant KRAS suppresses it in mice.
A short pre-surgery course of pembrolizumab left zero relapses in colorectal cancer patients after 33 months — reshaping treatment strategy.
A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.
A comprehensive review reveals how iron-driven cell death can be exploited to treat ATC, one of the most lethal human cancers.
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
A completed Phase II trial tests whether combining two checkpoint inhibitors can safely and effectively treat melanoma that has spread to the brain.
