Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization
2910 articles
Researchers critique BPC 157 peptide literature for single-center dominance, missing dose-response data, and unverified anticancer claims.
Researchers rebut claims that BPC 157 promotes tumor growth or neurodegeneration, citing evidence it modulates—not dysregulates—angiogenesis and NO.
The antioxidant peptide Epitalon restores wound healing in high-glucose-damaged retinal cells by curbing oxidative stress and fibrosis.
A 2025 comprehensive review maps how the AMPK/SIRT1/PGC-1α axis controls energy balance and drives neurodegeneration, diabetes, and cardiovascular disease.
A multicenter RCT of 440 patients finds albumin replacement safe but unable to significantly reduce mortality versus standard crystalloid care.
A comprehensive 2025 review covers GBS diagnosis, ICU management, immunotherapy, and emerging biomarkers for intensivists.
The 2025 ISTH guideline update elevates recombinant ADAMTS-13 as the preferred therapy for congenital TTP while maintaining prior immune TTP recommendations.
A 2025 JAMA review breaks down how plasma exchange, rituximab, and caplacizumab transformed survival in this rare blood-clotting emergency.
RA patients show accelerated immune aging in T cells, B cells, and myeloid cells—predating joint inflammation and directly fueling autoimmunity.
New research reveals autophagy's dual role in ferroptosis—sometimes triggering cell death, sometimes preventing it—depending on iron, lipid, and radical levels.
The Break Wave device shatters kidney stones into passable fragments in 7 of 10 patients, no anesthesia needed, in a clinic setting.
Health groups disagree on when to start mammograms. Here's how to navigate conflicting screening guidelines and make an informed decision.
