Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization
1309 articles
Anti-malarial drug artesunate significantly reduced kidney scarring in mice by restoring protective klotho protein and blocking fibrosis pathways.
New research explores how the longevity protein Klotho could revolutionize periodontitis diagnosis and treatment approaches.
Phase 1 trial shows blocking both GDF8 and activin A produces greater muscle gains than either alone in postmenopausal women.
90-day clinical trial shows natural oil blend significantly outperforms coconut oil for hair thickness, density, and regrowth.
New clinical review debunks widespread dehydration myths while highlighting serious risks for older adults requiring targeted prevention.
New review explores how targeted chemical compounds can rejuvenate aging skin stem cells without erasing cellular identity.
RepSox and tranylcypromine combination improved neurological markers and increased maximum lifespan in aging female mice.
New study reveals why promising chemical cocktails for cellular rejuvenation fail in living mice - dangerous fat accumulation.
Pyrroloquinoline quinone (PQQ) activates bone-building pathways and synergizes with teriparatide for stronger bones throughout life.
New research shows pyrroloquinoline quinone improves egg maturation and embryo development in animal models.
Single-cell analysis reveals PQQ reduces oxidative stress and restores immune function in aged mice through senolytic effects.
Researchers develop BH3 profiling to predict senolytic drug effectiveness, moving beyond one-size-fits-all aging treatments.
