Longevity & Aging
Blocked Mitophagy in Bone Cells Drives Kidney Disease Bone Loss
Uremic toxins impair mitochondrial cleanup in osteocytes, revealing new drug targets to protect bones in chronic kidney disease.
Research Paper
May 19, 2026 0
Research Topic
Longevity & Aging
Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization
2859 articles
Longevity & Aging
AI Maps ME/CFS Biology Linking Gut Microbes, Immunity and Metabolites to Symptoms
BioMapAI integrates five omics layers from 249 participants to classify ME/CFS and uncover gut-immune-metabolome drivers of heterogeneous symptoms.
Research Paper
May 19, 2026 0
Longevity & Aging
Chinese Immune Atlas Maps 10 Million Cells to Reveal Aging and Disease Secrets
The CIMA project profiles 10M+ immune cells from 428 adults, uncovering how sex, age, and genetics shape immune function at molecular resolution.
Research Paper
May 19, 2026 0
Longevity & Aging
Aging Muscles Preserve Mitochondrial Efficiency Despite Structural Remodeling
New mouse study finds mitochondrial energy coupling stays intact with age, but subtle structural losses and sarcopenia still limit performance.
Research Paper
May 19, 2026 0
Longevity & Aging
Intermittent Fasting Cuts Weight and Improves Heart Health in Overweight Adults
A 2025 meta-analysis of 15 RCTs finds IF significantly reduces body weight, BMI, and LDL cholesterol while lowering diastolic blood pressure.
Research Paper
May 19, 2026 0
Longevity & Aging
ERAS Society Updates 2025 Guidelines for Safer Cesarean Delivery Recovery
New evidence-based recommendations target antenatal and preoperative care to boost recovery outcomes for cesarean patients and their newborns.
Research Paper
May 19, 2026 0
Longevity & Aging
Diabetes Prevention Lasts 22 Years: Lifestyle Beats Metformin Long-Term
The landmark DPP trial shows lifestyle intervention delays diabetes onset by 3.5 years, metformin by 2.5 years, over two decades of follow-up.
Research Paper
May 19, 2026 0
Longevity & Aging
Intermittent Fasting Offers No Clear Edge Over Standard Dieting for Weight Loss
A Cochrane review of 22 RCTs finds intermittent fasting produces little to no additional weight loss compared to regular dietary advice or no intervention.
Research Paper
May 19, 2026 0
Longevity & Aging
Plant Flavonoid DMY Clears Senescent Cells and Eases Alzheimer's in Mice
Dihydromyricetin, found in vine tea, acts as a dual senotherapeutic—suppressing SASP in fibroblasts and eliminating senescent microglia in Alzheimer's mice.
Research Paper
May 19, 2026 0
Longevity & Aging
Thymosin Beta 4 Cuts Heart Damage After Heart Attacks in Mice and Humans
Recombinant human thymosin beta 4 reduces infarct size and cardiac dysfunction via ErbB2 signaling in both animal models and a clinical trial.
Research Paper
May 19, 2026 0
Longevity & Aging
Thymosin Beta 4 Reverses Alzheimer's Pathology in Human Brain Organoids and Mice
Scientists identify Tβ4 as a neuroprotective factor that rescues neuronal loss and amyloid buildup in both human fAD organoids and 5xFAD mice.
Research Paper
May 19, 2026 0
Longevity & Aging
FDA Opens Drug Repurposing Push to Tackle Chronic and Rare Disease Gaps
The FDA is seeking public input on repurposing approved drugs for new uses, targeting metabolic, neurodegenerative, and rare diseases.
Press Release
May 19, 2026 0