Research Topic

Longevity & Aging

Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization

1549 articles

Alpha-Lipoic Acid Plus Exercise Beats High-Fat Diet Damage, But Timing Matters
Longevity & Aging

Alpha-Lipoic Acid Plus Exercise Beats High-Fat Diet Damage, But Timing Matters

New study reveals combining antioxidant supplements with exercise provides superior protection against diet-induced aging, especially when started early.

Research Paper
Mar 29, 2026 2
Muscle Mass Protects Against Disease and Death Risk Across 46,000 Americans
Longevity & Aging

Muscle Mass Protects Against Disease and Death Risk Across 46,000 Americans

Major NHANES study reveals appendicular lean mass shields against multiple diseases and reduces mortality risk significantly.

Research Paper
Mar 29, 2026 2
Evening Sleep Patterns Linked to 12x Higher Heart Disease Death Risk in Older Adults
Longevity & Aging

Evening Sleep Patterns Linked to 12x Higher Heart Disease Death Risk in Older Adults

New study reveals how daily activity rhythms predict mortality risk, with evening chronotypes facing dramatically higher cardiovascular death rates.

Research Paper
Mar 29, 2026 2
Your Microbiome Changes Dramatically With Age and Affects Key Health Markers
Longevity & Aging

Your Microbiome Changes Dramatically With Age and Affects Key Health Markers

New research reveals how oral and gut bacteria shift across decades, influencing fatty acids and immune signals that impact aging.

Research Paper
Mar 29, 2026 2
AI Model Predicts Frailty Risk Using Medical Records With 78% Accuracy
Longevity & Aging

AI Model Predicts Frailty Risk Using Medical Records With 78% Accuracy

Japanese researchers developed machine learning to identify frail older adults using insurance claims, potentially revolutionizing early intervention.

Research Paper
Mar 29, 2026 2
New Cell Death Pathway Linked to Arthritis May Offer Treatment Target
Longevity & Aging

New Cell Death Pathway Linked to Arthritis May Offer Treatment Target

Scientists discover how disulfidptosis contributes to osteoarthritis and identify potential therapeutic compound.

Research Paper
Mar 29, 2026 3
AI Analysis Reveals Hidden Benefits in Failed Aging Study
Longevity & Aging

AI Analysis Reveals Hidden Benefits in Failed Aging Study

Machine learning uncovers subgroups who benefited from telecare despite overall null results in major aging trial.

Research Paper
Mar 29, 2026 2
Immune Cells Help Explain How GDF-15 Protein Drives Muscle Loss in Sarcopenia
Longevity & Aging

Immune Cells Help Explain How GDF-15 Protein Drives Muscle Loss in Sarcopenia

New research reveals how a specific immune cell type mediates the relationship between GDF-15 levels and muscle mass decline.

Research Paper
Mar 29, 2026 2
Resveratrol Disrupts Pancreatic Cancer Growth Through Novel Protein Modification
Longevity & Aging

Resveratrol Disrupts Pancreatic Cancer Growth Through Novel Protein Modification

New research reveals how resveratrol blocks pancreatic cancer progression by modifying a key cellular protein through succinylation.

Research Paper
Mar 29, 2026 2
Better Nutrition Status Protects Against Post-Surgery Cognitive Decline in Older Adults
Longevity & Aging

Better Nutrition Status Protects Against Post-Surgery Cognitive Decline in Older Adults

Study reveals nutritional assessment tool predicts cognitive complications after hip surgery in elderly patients.

Research Paper
Mar 29, 2026 2
Universal Oxidative Stress Responses Revealed Across All Animal Species
Longevity & Aging

Universal Oxidative Stress Responses Revealed Across All Animal Species

New research shows how oxidative stress damages cells similarly across all animals, from insects to mammals.

Research Paper
Mar 29, 2026 2
Gut Bacteria From Centenarians Reveal Secrets to Healthy Aging Through Epigenetic Control
Longevity & Aging

Gut Bacteria From Centenarians Reveal Secrets to Healthy Aging Through Epigenetic Control

New research shows how gut microbes in people over 100 produce metabolites that reprogram aging genes for better health and longevity.

Research Paper
Mar 29, 2026 2
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