Metabolic Health

SEC16B Gene Controls Blood Sugar Through Insulin-Producing Cells

New research reveals how SEC16B protein regulates glucose homeostasis by controlling insulin secretion in pancreatic beta cells.

New GLP-1 Drug Design Shows Superior Weight Loss in Mice

Novel GLP-1 analogue NNC5840 achieves greater weight reduction than semaglutide by optimizing receptor signaling bias rather than potency.

Bacterial Sulfur Sensors Control Denitrification in Wastewater Treatment

Two bacterial proteins that sense sulfur compounds unexpectedly regulate nitrate removal, revealing new targets for optimizing wastewater treatment.

New TyG-ABSI Index Outperforms Traditional Markers for Heart Disease Risk

Large NHANES study shows TyG-ABSI index better predicts cardiovascular disease and death in metabolic syndrome patients than standard measures.

Asia-Pacific Diabetes Advocacy Reveals Massive Healthcare Gaps Across 589M Patients

New review exposes stark disparities in diabetes care across Asia-Pacific, from insulin access to advanced technologies like CGM and pumps.

Scientists Map How Cholesterol Controls Cell Growth Through mTOR Pathway

New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.

FDA Approves Two New Weight Loss Drugs in Record Two-Week Span

Foundayo and Zepbound receive rapid FDA approval for chronic weight management in adults with obesity or weight-related conditions.

Drug Approval

Italian Nephrologists Survey Reveals Treatment Gaps in CKD Bone Disease Management

Survey of 89 Italian kidney specialists shows inconsistent approaches to treating bone disease in chronic kidney disease patients.

Metformin Plus MitoQ Combo Reverses Gulf War Illness Symptoms in Mice

Combined mitochondrial therapy restored muscle function and reduced fatigue in mouse model of Gulf War Illness.

Hexokinase Method Emerges as Gold Standard for Accurate Glucose Measurement

Comprehensive review reveals hexokinase method as the most precise technique for glucose testing in clinical laboratories.

Smart Biomaterials Use Electricity and Magnetism to Heal Diabetic Wounds

Electromagnetic biomaterials offer breakthrough approach to diabetic wound healing by reducing inflammation and promoting tissue regeneration.