Metabolic Health
GLP-1 Drugs Linked to 17–35% Lower Risk of Age-Related Macular Degeneration
A large retrospective study finds GLP-1 receptor agonists significantly reduce AMD risk in both diabetic and obese patients.
Research Paper
Jul 1, 2026 0
Research Topic
Metabolic Health
Insulin resistance, blood sugar regulation, metabolic syndrome, and body composition
455 articles
Metabolic Health
GLP-1 Drugs Show No Extra Depression Risk vs DPP-4 Inhibitors in Large Study
A 10-year Korean cohort study finds GLP-1 receptor agonists don't raise psychiatric risk compared to DPP-4 inhibitors, but show modest signals vs SGLT2 inhibitors.
Research Paper
Jul 1, 2026 0
Metabolic Health
Ginsenoside Rg1 Clears Brain Insulin Resistance by Boosting Hypothalamic Autophagy
A traditional Chinese formula and its key compound GsRg1 restore brain insulin signaling in obese rats by activating hypothalamic self-cleaning pathways.
Research Paper
Jun 30, 2026 0
Metabolic Health
Tirzepatide and Semaglutide Linked to Lower Anxiety and Depression in Obesity
A large real-world study finds GLP-1 drugs cut anxiety and depression risk vs. older weight-loss meds — but tirzepatide raises insomnia flags.
Research Paper
Jun 30, 2026 0
Metabolic Health
How Mitochondrial Quality Control Shapes Human Aging and Longevity
A new Nature Metabolism review reveals how mitochondrial maintenance systems govern healthy aging — and how NAD+, AMPK, and caloric restriction may restore them.
Review
Jun 30, 2026 0
Metabolic Health
Biosynthetic Semaglutide Cuts HbA1c by 1.86% and Weight by 7.8 kg in Real-World Use
A 30-week Pakistani multicentre study shows biosynthetic semaglutide delivers clinically meaningful glycemic and weight benefits in routine care.
Research Paper
Jun 29, 2026 0
Metabolic Health
GLP-1 Drugs May Restore Eye Surface Health While Reshaping Facial Anatomy
Semaglutide and liraglutide show promise for dry eye and corneal repair, but may cause periocular volume loss that affects blinking and tear distribution.
Review
Jun 29, 2026 0
Metabolic Health
Why Aging Fat Tissue Undermines Metabolism and How to Fix It
Aging adipose tissue loses its ability to generate new fat cells, driving insulin resistance. New review maps the molecular culprits and best treatment options.
Review
Jun 29, 2026 0
Metabolic Health
Lactate and Ketones Form a Hidden Redox Circuit Linking Organs and Fighting Disease
A new framework reveals how lactate and β-hydroxybutyrate team up across organs to regulate metabolism, mitochondria, and disease.
Review
Jun 29, 2026 0
Metabolic Health
GLP-1 Drugs Show Real Promise for Obese Kids and Teens With Type 2 Diabetes
A systematic review of 13 studies finds semaglutide and liraglutide meaningfully cut BMI and improve blood sugar in children and adolescents.
Review
Jun 29, 2026 0
Metabolic Health
GLP-1 Drugs and Muscle Loss: What the New Data Actually Shows
Peter Attia breaks down the real impact of Ozempic and Wegovy on muscle, bone, and physical function — and how to protect both.
Podcast
Jun 29, 2026 0
Metabolic Health
Semaglutide Cuts Appetite Without Dulling Taste, Mouse Study Finds
New research shows chronic semaglutide treatment causes weight loss while leaving taste perception fully intact, pointing to motivational rather than sensory mechanisms.
Research Paper
Jun 28, 2026 0