Insulin resistance, blood sugar regulation, metabolic syndrome, and body composition
455 articles
A 745-person genomic study identifies why metformin concentrations vary so widely — with ancestry-specific genetic variants playing a key role.
A randomized trial shows that extending overnight fasting by 3 hours, timed to sleep, cuts nighttime heart rate and improves glucose control.
New analysis finds delayed stomach emptying accounts for only 4–6% of appetite suppression from liraglutide, challenging a popular assumption.
A major review repositions type 2 diabetes as a proteinopathy, with amylin aggregation bridging metabolic decline and neurodegeneration.
A 16-week RCT finds metformin blocks exercise-induced improvements in artery and capillary function in adults at metabolic syndrome risk.
A completed clinical trial tests which dietary approach best controls extreme triglyceride levels in multifactorial chylomicronemia patients.
AICAR-driven AMPK activation rescues mitochondrial energy balance in hypoxic corneal cells, pointing to a new therapy for keratopathy.
New sensor data shows type 1 diabetics on ketogenic diets experience frequent, short-lived, asymptomatic ketosis episodes — mostly harmless.
A new review maps how tirzepatide's dual GIP/GLP-1 action reshapes metabolism across the pancreas, liver, gut, heart, kidneys, and brain.
People with schizophrenia exposed to the most nighttime light face 4x higher obesity odds and 3x higher hypertension odds.
A 5-year cohort study finds that CGM-derived time in range predicts arterial stiffness changes independently of HbA1c in type 2 diabetes.
Emerging evidence suggests GLP-1 receptor agonists like semaglutide may reduce cocaine craving and relapse by dampening dopamine signaling.
