Topic

Auto-Immunity

Autoimmune diseases, immune modulation, inflammation, and self-tolerance

203 articles

Gut Cell Energy Powerhouses Control Immune System Inflammation
Autoimmune & Arthritis

Gut Cell Energy Powerhouses Control Immune System Inflammation

Mitochondrial complex II in intestinal cells regulates T cell immune responses and inflammation pathways.

Research Paper
Mar 28, 2026 1
Scientists Map Complete Atlas of Brain Immune Cells Across 30 Disease States
Autoimmune & Arthritis

Scientists Map Complete Atlas of Brain Immune Cells Across 30 Disease States

Researchers analyzed over 1 million brain cells to create the first comprehensive map of microglia across diseases.

Research Paper
Mar 28, 2026 1
Tumor Macrophages Show Dual Nature That Could Transform Cancer Treatment
Autoimmune & Arthritis

Tumor Macrophages Show Dual Nature That Could Transform Cancer Treatment

New research reveals how immune cells in tumors can both fight and fuel cancer growth, opening paths to better therapies.

Research Paper
Mar 28, 2026 1
Scientists Discover Protein That Blocks Immune Cells From Fighting Cancer
Autoimmune & Arthritis

Scientists Discover Protein That Blocks Immune Cells From Fighting Cancer

New research reveals how removing ZFP148 protein boosts CD8+ T cells' cancer-fighting ability and improves immunotherapy response.

Research Paper
Mar 28, 2026 1
Circadian Rhythms Control Key Immune Cells Through Epigenetic Mechanisms
Autoimmune & Arthritis

Circadian Rhythms Control Key Immune Cells Through Epigenetic Mechanisms

New research reveals how our body clock regulates immune cell function through DNA modifications, offering insights for health optimization.

Research Paper
Mar 28, 2026 2
Inflammaging: How Chronic Inflammation Accelerates Aging
Autoimmune & Arthritis
Premium

Inflammaging: How Chronic Inflammation Accelerates Aging

Discover how persistent low-grade inflammation drives the aging process and learn strategies to combat this silent threat to longevity.

TutorialBeginner
Mar 28, 2026 4
New JAK3 Inhibitor ZL-82 Shows Promise for Rheumatoid Arthritis Treatment
Autoimmune & Arthritis

New JAK3 Inhibitor ZL-82 Shows Promise for Rheumatoid Arthritis Treatment

Phase I trial tests selective JAK3 inhibitor with improved safety profile compared to existing treatments for inflammatory conditions.

Clinical Trial
Mar 28, 2026 4
JAK Inhibitor Tofacitinib Shows Promise for Lupus Treatment in Safety Trial
Autoimmune & Arthritis

JAK Inhibitor Tofacitinib Shows Promise for Lupus Treatment in Safety Trial

Small NIH study tests oral drug tofacitinib as potential new treatment for systemic lupus erythematosus with fewer side effects.

Clinical Trial
Mar 28, 2026 4
Early Rheumatoid Arthritis Treatment Shows Promise for Rapid Remission
Autoimmune & Arthritis

Early Rheumatoid Arthritis Treatment Shows Promise for Rapid Remission

Small study tests whether tocilizumab can achieve faster, deeper remission in newly diagnosed rheumatoid arthritis patients.

Clinical Trial
Mar 28, 2026 3
New Drug KPL-404 Shows Promise for Treatment-Resistant Rheumatoid Arthritis
Autoimmune & Arthritis

New Drug KPL-404 Shows Promise for Treatment-Resistant Rheumatoid Arthritis

Phase 2 trial tests novel therapy for patients who failed standard biologics and JAK inhibitors in 145-person study.

Clinical Trial
Mar 28, 2026 3
New Rheumatoid Arthritis Drug Shows Promise for Treatment-Resistant Patients
Autoimmune & Arthritis

New Rheumatoid Arthritis Drug Shows Promise for Treatment-Resistant Patients

Phase 3 trial tests otilimab against standard care in 550 patients who failed previous biologics and JAK inhibitors.

Clinical Trial
Mar 28, 2026 3
JAK Inhibitor Shows Promise for Persistent Pain in Rheumatoid Arthritis Patients
Autoimmune & Arthritis

JAK Inhibitor Shows Promise for Persistent Pain in Rheumatoid Arthritis Patients

Small study explores how tofacitinib may address chronic pain that persists even when inflammation is controlled in RA patients.

Clinical Trial
Mar 28, 2026 3
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