Calcineurin Inhibitors Show Promise for Autoimmune Diseases Despite Toxicity Risks
Review examines immunosuppressive drugs like cyclosporine and tacrolimus, highlighting new applications and safety management strategies.
Autoimmune diseases, immune modulation, inflammation, and self-tolerance
202 articles
Review examines immunosuppressive drugs like cyclosporine and tacrolimus, highlighting new applications and safety management strategies.
New research reveals how IGF2BP3 protein promotes inflammation and tissue damage in rheumatoid arthritis through RNA modifications.
Expert commentary on pemphigus foliaceus, a rare autoimmune blistering disease affecting skin health and immune function.
Delphi study of 166 Italian neurologists establishes guidelines for individualized MS therapy based on patient needs and drug characteristics.
65 neurologists from 54 Italian MS centers agree on when and how to use high-efficacy therapies to prevent irreversible disability.
New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.
Comprehensive review explores how combining genomics, proteomics, and metabolomics advances psoriasis understanding and treatment.
New review reveals how immune cells orchestrate tissue scarring across organs, offering therapeutic targets for fibrosis affecting nearly a billion people.
New research reveals how lactate triggers lactylation, an epigenetic modification that fuels rheumatoid arthritis and lupus progression.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
Study reveals how gut microbes transform T cells into potent autoimmune drivers that migrate to joints and promote arthritis.
New research reveals how a mitochondrial enzyme enhances immune cell function to fight bacterial lung infections and reduce inflammation.