Autoimmune diseases, immune modulation, inflammation, and self-tolerance
202 articles
Specialized immune cells use antibodies to kill hepatitis B-infected cells, offering new targets for viral cure strategies.
Breakthrough immunotherapy approach demonstrates effectiveness in treating multiple autoimmune conditions simultaneously.
Groundbreaking study reveals how B cells acquire mutations in checkpoint genes to bypass immune tolerance in autoimmune thyroid disease.
International study of 1,200+ patients identifies clinical factors that predict sight-threatening complications in uveitis.
New research reveals how hepatitis B virus hijacks cellular machinery to suppress interferon signaling and evade immune detection.
New research reveals how fat tissue activates T cells, potentially explaining the link between obesity and inflammatory joint disease.
Icotrokinra, a breakthrough oral peptide targeting IL-23, demonstrates significant skin clearance in psoriasis with sustained benefits through 52 weeks.
Oral peptide targeting IL-23 receptor shows superior efficacy vs placebo and deucravacitinib in moderate-to-severe plaque psoriasis.
Clinical trial results for oral icotrokinra in treating plaque psoriasis across adult and adolescent patients published in NEJM.
New research reveals atopic dermatitis has multiple biological subtypes, each requiring personalized treatment approaches.
New spatial multiomics study maps cellular interactions in systemic sclerosis, revealing fibroblast-macrophage dynamics.
New research reveals how IL-35 therapy prevents neutrophil trap formation, offering hope for cigarette smoke-worsened asthma.
