Four Distinct Cancer Fibroblast Subtypes Shape Tumor Environment and Patient Survival
Massive spatial analysis reveals conserved fibroblast subtypes that control immune infiltration and therapy response across cancer types.
Latest breakthroughs in cancer research, treatment, and prevention
309 articles
Massive spatial analysis reveals conserved fibroblast subtypes that control immune infiltration and therapy response across cancer types.
New blood test identifies early-stage breast and lung cancers by measuring epigenetic chaos in cell-free DNA fragments.
Combination therapy with olaparib and irinotecan demonstrated activity in pediatric tumors, particularly those with genetic instability.
New study shows circulating tumor cells can predict treatment response and reveal drug resistance patterns.
Switching between different drug types prevents resistance in breast cancer therapy, offering hope for extended treatment options.
Large trial finds combination therapy doesn't improve survival or response rates compared to standard treatment alone.
Antibody-drug conjugate achieved 21% response rate in heavily pretreated patients with limited options.
Scientists identify TP53 and CYLD mutations that make HPV-positive head and neck cancers more aggressive and treatment-resistant.
Large study finds diabetes drug metformin only slightly slows harmful blood cell mutations, questioning its use for cancer prevention.
New study reveals combining PARP inhibitors with bevacizumab extends progression-free survival in previously treated ovarian cancer patients.
Study identifies blood markers that distinguish long-term survivors from short-term survivors in brain cancer treatment.
Ezabenlimab combined with chemotherapy and radiation therapy offers new treatment approach for stage 3 anal cancer patients.