Cancer Research
ISB 1442 Trial for Relapsed Multiple Myeloma Terminated Early
A first-in-human Phase 1/2 trial of ISB 1442 in relapsed/refractory multiple myeloma was halted before completion.
Clinical Trial
Jun 9, 2026 0
Topic
Cancer
Latest breakthroughs in cancer research, treatment, and prevention
643 articles
Cancer Research
CD226 Immune Receptor Explored as Predictor of Immunotherapy Response in Advanced Liver Cancer
A French trial investigated whether circulating immune cell profiles, specifically CD226 expression, could predict who responds to Atezolizumab/Bevacizumab in advanced HCC.
Clinical Trial
Jun 9, 2026 0
Cancer Research
Metronomic Vinorelbine Plus Atezolizumab Tested as Second-Line NSCLC Therapy
A completed Phase 2 trial explores whether low-dose continuous chemotherapy can boost immunotherapy efficacy in advanced lung cancer.
Clinical Trial
Jun 9, 2026 0
Cancer Research
Immunotherapy Plus T-DXd Shows Strong Results in HER2-Low Breast Cancer
The BEGONIA trial finds durvalumab combined with trastuzumab deruxtecan achieves 62% response rate in hard-to-treat metastatic breast cancer.
Research Paper
Jun 9, 2026 0
Cancer Research
Dormant Colorectal Cancer Cells Evade Chemo by Mimicking Embryonic Diapause
Cancer cells that downregulate SMC4 enter a low-proliferation, diapause-like state that resists standard chemotherapy, revealing a dangerous survival mechanism.
Research Paper
Jun 9, 2026 0
Cancer Research
GLP-1 Drugs Like Ozempic Linked to 30% Lower Breast Cancer Risk in Major Study
A study of 110,000+ women found GLP-1 users had ~30% lower breast cancer risk, sparking plans for clinical trials.
Press Release
Jun 7, 2026 0
Cancer Research
Statins Boost Chemotherapy Response in 70% of Advanced Pancreatic Cancer Patients
A 260-organoid biobank reveals statins target chemoresistant pancreatic cancer by disrupting cholesterol and glycosylation pathways.
Research Paper
Jun 7, 2026 0
Cancer Research
Leukemia Stem Cells Use Ketones to Dodge Cell Death and Fuel Disease
Leukemic stem cells produce their own ketone bodies to block ferroptosis, revealing a metabolic weak point that could be targeted therapeutically.
Research Paper
Jun 7, 2026 0
Cancer Research
Combo Immunotherapy Plus Liver Embolization Targets Metastatic Uveal Melanoma
A phase II trial tests ipilimumab and nivolumab paired with immunoembolization against liver-spread uveal melanoma.
Clinical Trial
Jun 6, 2026 0
Cancer Research
Skin Microbiome Shifts Detected in Immunotherapy Rash Patients
A City of Hope study explores whether skin bacteria differ between rash-affected and healthy skin in cancer immunotherapy patients.
Clinical Trial
Jun 6, 2026 0
Cancer Research
Hidden Cell Layers in Pancreatic Ducts Reveal Why Some Pancreatic Cancers Are Deadlier
Researchers mapped distinct cell populations in human pancreatic ducts, finding two subtypes that drive aggressive, lower-survival pancreatic cancer.
Research Paper
Jun 6, 2026 0
Cancer Research
Cancer's Immune Escape Trick Backfires by Opening a New Attack Route
When tumors hide from killer T cells, they accidentally expose themselves to helper T cells that trigger a lethal iron-driven cell death process.
Press Release
Jun 5, 2026 0