SGLT2 Inhibitors May Slow Aging by Clearing Senescent Cells
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
294 articles
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
A head-to-head review of 10 CGM devices for healthy adults, weighing real-world accuracy data against limited longevity evidence.
Three NIH-funded studies this week tackle metabolic decline, cardiac risk, and brain tumors — all with aging implications.
A major Cochrane network meta-analysis protocol will rank all insulin regimens by efficacy and safety for adults with type 1 diabetes.
A comprehensive review finds SGLT2 inhibitors reduce AKI risk in humans via hemodynamic, metabolic, and cellular protective pathways.
Expert reviews of top CGM platforms reveal genuine metabolic insights — but no proof they extend lifespan in healthy adults.
Wearable microneedle patches tap interstitial fluid to monitor glucose, lactate, and electrolytes in real time — no needles, no lab.
Go deeper into how AMPK detects energy stress, activates upstream kinases, and coordinates metabolism, autophagy, and longevity pathways at the molecular level.
Foundayo (orforglipron) becomes the first oral GLP-1 receptor agonist approved for obesity, offering a pill alternative to injectable Wegovy.