Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
294 articles
A novel conjugate merges GLP-1/GIP incretin signaling with pan-PPAR activation in one molecule, potentially revolutionizing metabolic therapy.
Discover AMPK — the master switch inside your cells that monitors energy levels and triggers powerful anti-aging responses when activated.
Six leading CGM platforms compared on accuracy, evidence quality, and longevity claims — most fall short of the hype.
Early bile acid and incretin responses after duodeno-ileal diversion may forecast long-term glycaemic outcomes in metabolic disease.
Men with T2D showed significantly greater postural instability after exercising in humid heat, despite normal thermoregulatory responses.
Combining cold exposure with exercise activates a key metabolic pathway to reduce liver fat and fibrosis more effectively than either intervention alone.
Continuous glucose monitors are popular in biohacking circles, but direct evidence linking CGM use to extended lifespan remains thin.
Huberman breaks down the neuroscience of sugar desire and shares practical tools to regulate blood glucose and curb cravings.
A deep mechanistic exploration of how ectopic lipid accumulation, mitochondrial dysfunction, mTOR-IRS1 feedback, and inflammatory crosstalk converge to drive age-related insulin resistance — plus emerging therapeutic strategies.
Go beyond the basics to explore the molecular machinery of insulin signaling — from receptor activation to GLUT4 translocation — and understand exactly how this cascade breaks down in insulin resistance and aging.
Explore how brown and beige fat activity declines with age, the metabolic ripple effects this creates, and the evidence-backed lifestyle strategies that can help restore thermogenic function.
Discover the three types of fat tissue in your body, what makes each one unique, and why activating the right kind could be a key to healthier aging.
