Topic

Heart Disease

Cardiovascular health, heart failure, atherosclerosis, and cardiac research

460 articles

NEJM Spotlights Hypertension as a Defining Cardiovascular Risk Factor
Heart Health

NEJM Spotlights Hypertension as a Defining Cardiovascular Risk Factor

A new NEJM perspective examines hypertension's central role in cardiovascular risk, with implications for prevention and clinical management.

Research Paper
May 23, 2026 0
Hidden Heart Risk: Microvascular Dysfunction Doubles Cardiac Event Rates
Heart Health

Hidden Heart Risk: Microvascular Dysfunction Doubles Cardiac Event Rates

A landmark Lancet registry finds coronary microvascular dysfunction raises major cardiac event risk by 91%, even after treating visible blockages.

Research Paper
May 23, 2026 0
Hidden Coronary Threat: Microvascular Dysfunction Drives Heart Disease Beyond Blocked Arteries
Heart Health

Hidden Coronary Threat: Microvascular Dysfunction Drives Heart Disease Beyond Blocked Arteries

A Lancet review spotlights how small vessel dysfunction silently worsens atherosclerotic coronary disease, reshaping diagnosis and treatment.

Research Paper
May 23, 2026 0
Diet Alone Can Cut LDL by 30% and Rival Blood Pressure Drugs
Heart Health

Diet Alone Can Cut LDL by 30% and Rival Blood Pressure Drugs

Simon Hill's cardiovascular masterclass covers the Portfolio Diet, plaque regression, ApoB testing, and the sodium-potassium ratio with top experts.

Podcast
May 22, 2026 0
High Fitness in Youth Protects the Heart Despite Slight Atrial Fibrillation Risk
Heart Health

High Fitness in Youth Protects the Heart Despite Slight Atrial Fibrillation Risk

A million-man study finds that adolescent cardiorespiratory fitness delivers net cardiovascular benefits that far outweigh any AF risk.

Research Paper
May 22, 2026 0
Heart Enzyme PYGM Shields Against Heart Attack by Boosting Energy and Autophagy
Heart Health

Heart Enzyme PYGM Shields Against Heart Attack by Boosting Energy and Autophagy

A muscle enzyme that declines in heart attack patients may hold the key to preserving cardiac function after MI.

Research Paper
May 21, 2026 0
Two-Year Plant-Based Supplement Trial for Inflammaging in Overweight Seniors Terminated Early
Heart Health

Two-Year Plant-Based Supplement Trial for Inflammaging in Overweight Seniors Terminated Early

A 2-year clinical trial testing Juice Plus+ products against low-grade inflammation and biological aging markers in overweight seniors was terminated before completion.

Clinical Trial
May 20, 2026 0
Inflammaging Biomarkers Causally Reshape Retinal Vessels and Predict Cardiovascular Fate
Heart Health

Inflammaging Biomarkers Causally Reshape Retinal Vessels and Predict Cardiovascular Fate

Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan — establishing causal direction.

Research Paper
May 20, 2026 0
How Your Heart Ages and What Science Can Do to Slow It Down
Heart Health

How Your Heart Ages and What Science Can Do to Slow It Down

A 2025 review maps the molecular mechanisms driving cardiovascular aging—from inflammaging to ECM remodeling—and outlines emerging therapies.

Research Paper
May 20, 2026 0
NR Supplementation Tested as Cardiac Rescue in Systolic Heart Failure Patients
Heart Health

NR Supplementation Tested as Cardiac Rescue in Systolic Heart Failure Patients

A Phase 1/2 trial tests whether nicotinamide riboside can restore NAD+ balance and improve heart function in systolic HF patients.

Clinical Trial
May 20, 2026 0
Social Adversity Quadruples Mortality Risk in HIV Patients With Heart Failure
Heart Health

Social Adversity Quadruples Mortality Risk in HIV Patients With Heart Failure

A NYC cohort study finds social adversity dramatically raises mortality and rehospitalization in people living with HIV and heart failure.

Research Paper
May 20, 2026 0
Evolocumab Cuts Heart Attack Risk 50% in PCI Patients Without Prior MI
Heart Health

Evolocumab Cuts Heart Attack Risk 50% in PCI Patients Without Prior MI

A major trial shows evolocumab dramatically reduces cardiovascular events in stent patients who've never had a heart attack.

Research Paper
May 20, 2026 0
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