Cardiovascular health, heart failure, atherosclerosis, and cardiac research
460 articles
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Cas13-based RNA editing shows promise for treating hereditary hypertrophic cardiomyopathy by correcting disease-causing mutations at the RNA level.
A Circulation review from Harvard proposes the 'target trial framework' to improve how observational data is used to assess cardiovascular device safety and effectiveness.
A Swedish cohort of 4.3 million found maternal diabetes during pregnancy significantly increases offspring CVD risk, with pregestational diabetes driving the highest hazard.
A pathological study ties common Lp(a) risk gene variants to specific coronary thrombosis morphologies in sudden cardiac death victims.
A newly funded NIH study introduces improved predictive measures for a chronic heart condition, potentially reshaping clinical risk assessment.
In obese middle-aged mice, reducing dietary protein—without cutting calories—reversed cardiac inflammation and remodeling via AMPK-ULK1 mitophagy.
Laroprovstat, a once-daily pill, slashed LDL by 80% when combined with rosuvastatin — rivaling injectable PCSK9 inhibitors.
A landmark Circulation review reveals how aging blood vessels accelerate systemic decline — and outlines emerging therapies to stop it.
The American Heart Association's 2026 update outlines evidence-based strategies to slow disease progression and protect grafts after CABG.
The PRINCE trial investigators address scientific critiques of their landmark study on cardiac protection during noncardiac surgery.
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
