Topic

Reversing Aging

Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions

1,775 articles

Bryan Johnson Announces a New Medical Diagnosis
Longevity & Aging

Bryan Johnson Announces a New Medical Diagnosis

Bryan Johnson announces he has received a medical diagnosis and says he is eager to take it on. Specifics are not available from the provided source.

Video
Jul 7, 2026 0
SenFlag Signature Reliably Spots Senescent Cells Across Mouse and Human Tissues
Longevity & Aging

SenFlag Signature Reliably Spots Senescent Cells Across Mouse and Human Tissues

A new gene signature called SenFlag precisely identifies senescent cells in single-cell data, tracking their accumulation with age and injury.

Research Paper
Jul 7, 2026 0
Pancreatic Neuroendocrine Tumors Explained From Diagnosis to Treatment
Longevity & Aging

Pancreatic Neuroendocrine Tumors Explained From Diagnosis to Treatment

A comprehensive review of pNETs covers genetics, clinical syndromes, imaging, and evolving therapies with 90% survival in low-grade cases.

Research Paper
Jul 6, 2026 0
SRN-901 Combo Drug Extends Mouse Lifespan 33% and Slashes Frailty in Late-Life Trial
Longevity & Aging

SRN-901 Combo Drug Extends Mouse Lifespan 33% and Slashes Frailty in Late-Life Trial

A five-compound oral drug targeting mTOR, autophagy, NAD+, and senescence extended median lifespan 33% and cut frailty progression 70% in aged mice.

Research Paper
Jul 6, 2026 0
Sestrins in Depth: Molecular Switches Between Stress and Longevity
Longevity & Aging
Premium

Sestrins in Depth: Molecular Switches Between Stress and Longevity

Go beyond the basics and explore how sestrins work at the molecular level — regulating AMPK, mTORC1, and autophagy to coordinate your cell's response to stress and aging.

TutorialIntermediate
Jul 6, 2026 0
Nature Aging Highlights Molecular Aging Changes That Appear Exercise-Independent
Longevity & Aging

Nature Aging Highlights Molecular Aging Changes That Appear Exercise-Independent

A short Nature Aging item flags that some age-related molecular changes appear to occur independently of exercise. Only the title is available; details await full-text review.

Research Paper
Jul 6, 2026 0
Why Greenland Sharks Live 400 Years and What It Means for Human Aging
Longevity & Aging

Why Greenland Sharks Live 400 Years and What It Means for Human Aging

A new review unpacks the molecular and physiological secrets behind the world's longest-lived vertebrate.

Review
Jul 6, 2026 0
How Metabolic Kinases Control Organelle Teamwork in Aging and Disease
Longevity & Aging

How Metabolic Kinases Control Organelle Teamwork in Aging and Disease

Key enzymes like AMPK and mTOR orchestrate communication between cellular organelles — and their failure may drive aging and neurodegeneration.

Review
Jul 6, 2026 0
How Reprogramming Aging Cells Could Supercharge Cancer Immunotherapy
Longevity & Aging

How Reprogramming Aging Cells Could Supercharge Cancer Immunotherapy

A major review reveals how cellular senescence and biological aging clocks intersect to reshape cancer immunity and treatment strategy.

Research Paper
Jul 5, 2026 0
Epigenetic Editing Moves From Lab Bench to Human Clinical Trials
Longevity & Aging

Epigenetic Editing Moves From Lab Bench to Human Clinical Trials

A landmark review traces how epigenetic editing — rewriting gene expression without touching DNA — is entering its first clinical trials.

Research Paper
Jul 5, 2026 0
Vagus Nerve Stimulation Expands Beyond Epilepsy Into Inflammation and Depression
Longevity & Aging

Vagus Nerve Stimulation Expands Beyond Epilepsy Into Inflammation and Depression

VNS is FDA-approved for epilepsy and depression, and emerging research targets autoimmune and chronic inflammatory conditions.

Research Paper
Jul 5, 2026 0
Your Body's Hidden Stress Shields: An Introduction to Sestrins
Longevity & Aging
Premium

Your Body's Hidden Stress Shields: An Introduction to Sestrins

Meet sestrins — the remarkable proteins your cells make when under stress that may hold the key to healthier, longer aging. No science degree required.

TutorialBeginner
Jul 5, 2026 0
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