Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,795 articles
Adults 80+ who walk as fast as 50-year-olds show dramatically lower dementia risk and preserved brain volume, new multi-cohort data reveals.
Heliconius butterflies live up to 25x longer than relatives and show no physical decline — scientists want to know why.
Scientists discover R-loops in senescent cells trigger inflammatory secretions, linking a transcription glitch to a key aging mechanism.
Human Longevity Inc drops genome sequencing to $599, combining DNA with AI and multi-omics to flag disease risk before symptoms appear.
New research reveals how aging transforms protective immune cells into drivers of inflammation, senescence, and tissue damage.
A new Nature Communications study identifies NRF1 as a master driver of inflammaging via the TBK1/IRF3 innate immune axis.
A new review maps the molecular mechanisms behind liver aging and evaluates dietary, drug, and gene-editing interventions to slow decline.
A Nature Aging perspective asks whether GLP-1 receptor agonists like semaglutide are true anti-aging therapies or simply metabolic drugs.
Exosomes from young human plasma outperform older plasma exosomes at rebuilding bone, with miR-142-5p identified as the key molecular driver.
Master the full systems-level view of polyamine biology — from biosynthetic flux control and post-translational modifications to clinical trial design and emerging therapeutic strategies.
A 12-year Yale study of 11,000+ adults reveals 45% improved cognitively or physically after 65 — and positive aging beliefs drove the gains.
Researchers found 12 rare genetic variants in long-lived families, including one in the CGAS gene that may reduce chronic inflammation and delay disease.
