Topic

Reversing Aging

Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions

667 articles

Aging Fat Tissue Drives Disease Risk But New Therapies Show Promise
Longevity & Aging

Aging Fat Tissue Drives Disease Risk But New Therapies Show Promise

Review reveals how adipose tissue changes with age affect metabolism and lifespan, plus potential interventions to combat aging.

Research Paper
Mar 31, 2026 0
New Drugs Target Zombie Cells to Fight Aging and Age-Related Disease
Longevity & Aging

New Drugs Target Zombie Cells to Fight Aging and Age-Related Disease

Scientists review promising therapies that eliminate or control senescent cells to promote healthier aging and prevent disease.

Research Paper
Mar 31, 2026 0
CAR T-Cell Therapy Shows Promise for Treating Liver Disease and Extending Healthspan
Longevity & Aging

CAR T-Cell Therapy Shows Promise for Treating Liver Disease and Extending Healthspan

Engineered immune cells could revolutionize treatment of liver diseases, fibrosis, and age-related cellular damage.

Research Paper
Mar 31, 2026 0
Scientists Map Strategy to Reverse Heart Aging and Extend Cardiovascular Health
Longevity & Aging

Scientists Map Strategy to Reverse Heart Aging and Extend Cardiovascular Health

Researchers outline comprehensive roadmap targeting age-related cardiovascular decline through emerging therapeutic approaches.

Research Paper
Mar 31, 2026 0
Aging and Injury Trigger Senescent Neurons in Pain-Processing Centers
Longevity & Aging

Aging and Injury Trigger Senescent Neurons in Pain-Processing Centers

Study reveals how aging and nerve injury create inflammatory senescent neurons in dorsal root ganglia, potentially driving chronic pain in older adults.

Research Paper
Mar 31, 2026 0
Nano-Adjuvant Reverses Age-Related Muscle Loss Through Mitochondrial Restoration
Longevity & Aging

Nano-Adjuvant Reverses Age-Related Muscle Loss Through Mitochondrial Restoration

Novel nanoparticle therapy targets sarcopenia by restoring mitochondrial function and enhancing muscle-immune cell communication.

Research Paper
Mar 31, 2026 0
Urolithin A Blocks Inflammatory Aging Signals by Targeting DNA Leakage in Senescent Cells
Longevity & Aging

Urolithin A Blocks Inflammatory Aging Signals by Targeting DNA Leakage in Senescent Cells

Pomegranate metabolite urolithin A reduces harmful inflammatory signals from aging cells by preventing DNA leakage and blocking cGAS-STING pathway.

Research Paper
Mar 31, 2026 0
Urolithin A Protects Female Fertility from Chemotherapy Damage
Longevity & Aging

Urolithin A Protects Female Fertility from Chemotherapy Damage

Gut metabolite preserves ovarian reserve by blocking harmful signaling pathways and preventing follicle death during cancer treatment.

Research Paper
Mar 31, 2026 0
Novel Raman Imaging Reveals How TJ0113 Drug Rescues Liver Failure Through Mitophagy
Longevity & Aging

Novel Raman Imaging Reveals How TJ0113 Drug Rescues Liver Failure Through Mitophagy

Breakthrough study uses label-free Raman spectroscopy to track mitochondrial repair in real-time during acute liver failure treatment.

Research Paper
Mar 31, 2026 0
Urolithin A Restores Cellular Communication to Promote Healthy Aging
Longevity & Aging

Urolithin A Restores Cellular Communication to Promote Healthy Aging

Gut metabolite urolithin A enhances mitochondrial quality control through calcium signaling, extending lifespan in worms and protecting human cells.

Research Paper
Mar 31, 2026 0
Urolithin A Supplement Reverses Age-Related Immune Decline in Middle-Aged Adults
Longevity & Aging

Urolithin A Supplement Reverses Age-Related Immune Decline in Middle-Aged Adults

Four-week trial shows mitophagy inducer urolithin A expands youthful T cells and improves immune metabolism in healthy adults aged 45-70.

Research Paper
Mar 31, 2026 0
Major Dog Aging Trial Tests Rapamycin for Extending Lifespan and Healthspan
Longevity & Aging

Major Dog Aging Trial Tests Rapamycin for Extending Lifespan and Healthspan

Groundbreaking multicenter trial will test rapamycin's ability to extend healthy lifespan in companion dogs, offering insights for human aging.

Research Paper
Mar 31, 2026 0
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