Longevity & Aging
How Your Immune System Ages and Why It Drives Most Age-Related Disease
A landmark 2025 review maps how every major immune compartment changes with age—and what goes wrong before disease strikes.
Research Paper
Jun 21, 2026 0
Topic
Reversing Aging
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,795 articles
Longevity & Aging
Natural Compounds Target Multiple Aging Pathways as AI Accelerates Discovery
A 2025 review maps how polyphenols, terpenoids, and marine metabolites modulate Nrf2, mTOR, SIRT1, and AMPK to slow aging—and how AI is speeding up the search.
Research Paper
Jun 21, 2026 0
Longevity & Aging
N-Glycopedia Gives Researchers a 226-Glycan Atlas to Decode Protein Sugar Coats
A landmark library of 226 N-glycan standards with mass spec data could transform glycoproteomics and disease biomarker discovery.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Aging Brain Neurons Send Signals That Destroy Bone Density
A protein called WDFY1, released by aged brain neurons via tiny vesicles, travels to bone and drives osteoporosis and marrow fat accumulation.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Why Your Arteries Stiffen With Age and How to Fight Back
A landmark 2025 review maps every mechanism behind arterial stiffness—and charts a clear path toward prevention and therapy.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Mitochondria Are the Master Key to Healthy Aging and Disease Prevention
A landmark editorial synthesizes how mitochondrial decline drives aging, neurodegeneration, and heart disease—and how new therapies may reverse it.
Research Paper
Jun 21, 2026 0
Longevity & Aging
How Aging and Blood Flow Mechanics Drive Metabolic Breakdown in Artery Walls
A comprehensive review reveals how aging and disturbed blood flow reprogram endothelial cell metabolism, fueling atherosclerosis through glycolytic, lipid, and mitochondrial dysregulation.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Young Mitochondria Transferred Between Ovarian Cells Reverse Reproductive Aging
Researchers restored aging ovarian cell function by reactivating mitochondrial sharing via tunneling nanotubes, using FTY720 and 3D scaffolds.
Research Paper
Jun 21, 2026 0
Longevity & Aging
How Aging Granulosa Cells Undermine Egg Quality and What We Can Do About It
New review reveals how aging disrupts the support cells surrounding eggs, offering therapeutic targets to preserve female fertility.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Premium
Spermidine, Autophagy, and the Molecular Clock: How Polyamines Regulate Aging
Go beyond the basics and explore the precise molecular mechanisms by which polyamines slow cellular aging — from autophagy induction to epigenetic regulation and cardiovascular protection.
TutorialIntermediate
Jun 21, 2026 0
Longevity & Aging
Geroscience Roadmap Targets Aging Biology to Prevent Multiple Diseases at Once
A landmark review synthesizes 12 hallmarks of aging, emerging gerotherapeutics, and a new three-tier clinical care model to shift medicine from disease treatment to aging prevention.
Research Paper
Jun 21, 2026 0
Longevity & Aging
Metformin Targets Aging and Cancer Through Seven Interconnected Pathways
A comprehensive review reveals metformin's polypharmacological mechanisms—from AMPK activation to gut microbiome remodeling—that may delay aging and enhance cancer immunotherapy.
Research Paper
Jun 21, 2026 0