Longevity & Aging
Late-Life Gene Therapy Extends Mouse Lifespan 20% by Boosting Metabolism
A single FGF21 gene injection in aging mice extended median lifespan by 20%, reversing fat gain, inflammation, and organ decline.
Press Release
Jun 17, 2026 0
Topic
Reversing Aging
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,795 articles
Longevity & Aging
FDA Fast-Tracks New NLRP3 Drug Showing 67% Response Rate in Bone Marrow Disorder
Ofirnoflast targets inflammasome activation in myelodysplastic syndromes, with 56% of transfusion-dependent patients achieving independence.
Press Release
Jun 17, 2026 0
Longevity & Aging
SonoThera's $125M Ultrasound Platform Could Unlock Repeatable Gene Therapy for Aging
SonoThera raises $125M to advance ultrasound-based gene delivery that bypasses viral limits, enabling repeat dosing critical for longevity therapies.
Press Release
Jun 17, 2026 0
Longevity & Aging
Crowdfunding Campaign Targets the Underfunded Science of Ovarian Aging
The Longevity Science Foundation's $250K campaign aims to fund ovarian aging research linking menopause to heart, brain, and bone health.
Press Release
Jun 17, 2026 0
Longevity & Aging
R-Loop Export Drives Inflammaging — and Blocking It Extends Healthspan
Scientists identify a novel molecular pathway linking nuclear R-loops to chronic age-related inflammation, with a druggable target already in clinical use.
Research Paper
Jun 17, 2026 0
Longevity & Aging
New Synthetic Flavonol Clears Senescent Cells and Reverses Lung Fibrosis in Mice
A medicinal-chemistry optimized flavonol called F-4N shows 50× greater senolytic potency than quercetin and resolves lung fibrosis in animal models.
Research Paper
Jun 16, 2026 0
Longevity & Aging
Lancet 2026 Seminar Declares a New Era in Alzheimer's Management
A landmark Lancet review charts exponential progress in AD biomarkers, imaging, genetics, and treatment — while mapping what still needs to be conquered.
Research Paper
Jun 16, 2026 0
Longevity & Aging
Disease Burden in the 95+ Population Has Quintupled Since 1990
A sweeping 33-year global analysis reveals cardiometabolic and neurodegenerative diseases dominate health loss in the fastest-growing age group.
Research Paper
Jun 16, 2026 0
Longevity & Aging
IGFBP2 Protein Loss Drives Uterine Cell Aging Behind Thin Endometrium
Researchers identify IGFBP2 downregulation as a key driver of endometrial cell senescence, opening new therapeutic targets for thin endometrium.
Research Paper
Jun 16, 2026 0
Longevity & Aging
NAD+ Depletion in Brain Blood Vessels Sparks Alzheimer's Neuroinflammation
A new study reveals how amyloid beta drains NAD+ from brain endothelial cells, triggering a mitochondrial DNA–innate immune cascade that inflames the aging brain.
Research Paper
Jun 16, 2026 0
Longevity & Aging
Mitochondria Are Aging Clocks Through Signaling, Not Just Energy Failure
New review argues aging stems from disrupted mitochondrial signaling, not ATP loss—and mild complex I inhibition may extend healthspan.
Research Paper
Jun 16, 2026 0
Longevity & Aging
Premium
Genomic Chaos: The Systems Biology of Transposable Element-Driven Aging
A rigorous mechanistic deep-dive into how transposable element reactivation drives aging at the molecular level — from chromatin topology disruption to therapeutic intervention strategies.
TutorialAdvanced
Jun 16, 2026 0