Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,802 articles
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
A prominent biologist argues preclinical aging research needs a reality check to better translate animal findings into human longevity gains.
Combining mesenchymal stem cell transplantation with exercise may overcome key limitations of standalone therapy for sarcopenia.
Go deeper into the mechanisms by which reactivated transposable elements damage DNA, trigger inflammation, and accelerate aging — and what biology is doing to fight back.
New NIH research challenges the popular idea that taurine levels reliably track biological aging, raising questions for supplement advocates.
A comprehensive 2025 review maps the mechanisms, clinical evidence, and public health implications of functional foods for chronic disease prevention.
A 2025 review maps the full biology of hair graying—from oxidative stress to stem cell loss—and evaluates emerging prevention and treatment options.
Discover how ancient 'jumping genes' hidden in your DNA can wake up as you age, cause chaos in your cells, and what scientists are learning about stopping them.
Once dismissed as normal aging, white matter lesions are now confirmed neuroimaging markers predicting stroke, dementia, and death.
A 1,030-person lipidomic study uncovers three distinct aging 'crests' and sex-divergent lipid shifts that reshape how we understand biological aging.
Qi-Gu capsule activates the HIF-1α/AMPK pathway to reduce oxidative stress and stem cell senescence, restoring bone density in preclinical models.
A deep mechanistic examination of mitophagy's molecular circuitry — from ubiquitin chain topology to mitochondrial-nuclear crosstalk — and the emerging therapeutic strategies targeting this pathway to slow aging.
