Topic

Reversing Aging

Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions

669 articles

Four Endogenous Metabolites Show Promise for Extending Human Lifespan
Longevity & Aging

Four Endogenous Metabolites Show Promise for Extending Human Lifespan

Review identifies taurine, betaine, α-ketoglutarate, and other naturally-produced compounds that may delay aging through multiple cellular pathways.

Research Paper
Mar 29, 2026 1
Epigenetic Clocks Could Revolutionize Personalized Anti-Aging Skin Treatments
Longevity & Aging

Epigenetic Clocks Could Revolutionize Personalized Anti-Aging Skin Treatments

New research shows biological age markers can guide personalized aesthetic treatments that target aging at the molecular level.

Research Paper
Mar 29, 2026 1
Aging Immune System Drives Cancer Growth and Therapy Resistance
Longevity & Aging

Aging Immune System Drives Cancer Growth and Therapy Resistance

Comprehensive review reveals how immunosenescence creates tumor-promoting environments and reduces treatment effectiveness in elderly cancer patients.

Research Paper
Mar 29, 2026 1
Rapamycin Shows Promise for Longevity But Safety Concerns Remain for Healthy Adults
Longevity & Aging

Rapamycin Shows Promise for Longevity But Safety Concerns Remain for Healthy Adults

Comprehensive review examines rapamycin's anti-aging potential, revealing mixed results and significant safety considerations for off-label use.

Research Paper
Mar 29, 2026 1
Senolytics Show Promise for Osteoporosis But Clinical Results Lag Behind Lab Studies
Longevity & Aging

Senolytics Show Promise for Osteoporosis But Clinical Results Lag Behind Lab Studies

New review examines senolytic drugs that target aging cells in bone tissue, revealing gaps between promising animal studies and human trials.

Research Paper
Mar 29, 2026 1
Cellular Senescence Shows Dual Role in Cancer: Tumor Suppressor and Promoter
Longevity & Aging

Cellular Senescence Shows Dual Role in Cancer: Tumor Suppressor and Promoter

New review reveals how senescent cells both prevent and fuel cancer, opening doors to precision therapies targeting aging pathways.

Research Paper
Mar 29, 2026 1
Senolytics and Senomorphics Show Promise for Targeting Aging at the Cellular Level
Longevity & Aging

Senolytics and Senomorphics Show Promise for Targeting Aging at the Cellular Level

Comprehensive review reveals how drugs that eliminate or modify senescent cells could revolutionize anti-aging medicine.

Research Paper
Mar 29, 2026 4
AI Agents Discover Anti-Aging Drugs by Mining 2 Million Molecular Profiles
Longevity & Aging

AI Agents Discover Anti-Aging Drugs by Mining 2 Million Molecular Profiles

Autonomous AI system reanalyzed millions of studies to find 500+ interventions that reduce biological age, validating ouabain in mice.

Research Paper
Mar 29, 2026 1
ACBP Protein Drives Aging by Blocking Autophagy, Antibody Treatment Reverses Damage
Longevity & Aging

ACBP Protein Drives Aging by Blocking Autophagy, Antibody Treatment Reverses Damage

Centenarians have 3x higher ACBP levels. Blocking this aging protein with antibodies prevents organ damage and cellular senescence.

Research Paper
Mar 29, 2026 1
Multi-Organ Aging Study Reveals Why People Age at Different Rates
Longevity & Aging

Multi-Organ Aging Study Reveals Why People Age at Different Rates

New research explores how aging varies across organ systems using comprehensive molecular analysis to understand individual differences.

Research Paper
Mar 29, 2026 1
Scientists Map How Metabolism Changes Across 12 Organs During Aging
Longevity & Aging

Scientists Map How Metabolism Changes Across 12 Organs During Aging

Comprehensive study reveals metabolic aging patterns across organs and identifies compounds that could slow aging processes.

Research Paper
Mar 29, 2026 1
Low-Dose Pesticide Exposure Accelerates Aging and Shortens Lifespan in Wild Fish
Longevity & Aging

Low-Dose Pesticide Exposure Accelerates Aging and Shortens Lifespan in Wild Fish

Chronic exposure to low levels of chlorpyrifos pesticide causes telomere shortening and premature aging in fish populations.

Research Paper
Mar 29, 2026 1
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