Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,805 articles
A large UK Biobank study reveals biological aging mediates up to 27% of lifestyle-driven colorectal cancer risk, with DNA methylation changes at 15 CpG sites as key mechanisms.
A systematic review of 73 studies finds HIV strongly linked to shorter telomeres, suggesting infections may accelerate biological aging.
A 2026 review of 32 human studies identifies which supplements genuinely support muscle, brain, metabolism, and immunity as we age.
Go beneath the surface to explore how CLOCK, BMAL1, and their molecular partners drive your circadian rhythm — and why disrupting them accelerates cellular aging.
A large study confirms current CKD diagnostic thresholds hold up under gold-standard kidney testing, while revealing which biomarker combo predicts risk best.
A 9-year longitudinal study links high ultraprocessed food intake to sharply higher dementia and cognitive impairment risk in older adults.
Cambrian Bio's ATX-304 combines AMPK and mitochondrial activation in a pill form, with Phase 1b data in prediabetic obese adults due this week.
A landmark Cell study builds layered biological age clocks from 2,019 people, pinpointing coagulation proteins as unexpected aging drivers.
A retiring editor of Aging Cell shares insights on where the science of aging is heading and what geroscience still needs to achieve.
A newly identified protein called LYVAC controls how lysosomes swell under stress, with implications for aging, neurodegeneration, and chemotherapy resistance.
A new review identifies protein, NAD⁺ precursors, antioxidants, and probiotics as top evidence-backed supplements for aging adults.
A new review synthesizes evidence that combined glycine and NAC supplementation, especially with exercise, tackles oxidative stress, mitochondrial decline, and muscle loss in older adults.
