Topic

Reversing Aging

Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions

1,805 articles

Ancient Herb Shields Aging Kidneys by Neutralizing Oxidative Stress
Longevity & Aging

Ancient Herb Shields Aging Kidneys by Neutralizing Oxidative Stress

Dendrobium officinale extract protects aging kidneys by activating antioxidant defenses through a key cellular signaling pathway.

Research Paper
May 26, 2026 0
UCHL1 Shields Spinal Disc Cells From Aging Via a Novel Autophagy-Ferroptosis Switch
Longevity & Aging

UCHL1 Shields Spinal Disc Cells From Aging Via a Novel Autophagy-Ferroptosis Switch

A deubiquitinase stabilizes a key chaperone protein to activate protective autophagy and block iron-driven cell death in spinal discs.

Research Paper
May 26, 2026 0
PRDM16 Protein Fights Cellular Aging by Activating a Key Antioxidant Gene
Longevity & Aging

PRDM16 Protein Fights Cellular Aging by Activating a Key Antioxidant Gene

Scientists discover PRDM16 declines in aged organs and its loss accelerates senescence; restoring it via GSTM1 may slow organ aging.

Research Paper
May 26, 2026 0
Omega-3 Fatty Acids Shown to Reduce Kidney Cell Aging and Fibrosis in New Study
Longevity & Aging

Omega-3 Fatty Acids Shown to Reduce Kidney Cell Aging and Fibrosis in New Study

New research reveals omega-3s activate a receptor that curbs cellular senescence and fibrosis in kidneys, pointing to a clear biological mechanism.

Press Release
May 26, 2026 0
FDA-Cleared Home Sleep Device Tests Multiple Nights to Catch Hidden Apnea
Longevity & Aging

FDA-Cleared Home Sleep Device Tests Multiple Nights to Catch Hidden Apnea

Sunrise Air ditches clinic wires for a chin-worn sensor that tracks sleep apnea across multiple nights at home.

Press Release
May 26, 2026 0
Open-Source AI Tool Audits Longevity Research to Eliminate Hallucinations
Longevity & Aging

Open-Source AI Tool Audits Longevity Research to Eliminate Hallucinations

Forever Healthy's AI4L framework uses adversarial AI agents to verify every claim and citation in longevity evidence reviews.

Press Release
May 26, 2026 0
Retro Biosciences Hits $1.8B Valuation Advancing Human Lifespan Extension
Longevity & Aging

Retro Biosciences Hits $1.8B Valuation Advancing Human Lifespan Extension

Sam Altman-backed Retro Biosciences enters clinical trials with a drug targeting Alzheimer's protein clumps, aiming to add 10 healthy years to human life.

Press Release
May 26, 2026 0
Common Immune Gene Variant Cuts Male Longevity Odds by 36 Percent
Longevity & Aging

Common Immune Gene Variant Cuts Male Longevity Odds by 36 Percent

A multi-cohort study finds HLA-DRB1*15:01 significantly reduces longevity likelihood in northern European men, possibly via Alzheimer's and immune reactivity to LDL.

Research Paper
May 26, 2026 0
Serine Metabolism Breakdown Drives Kidney Aging — And Fixing It May Slow CKD
Longevity & Aging

Serine Metabolism Breakdown Drives Kidney Aging — And Fixing It May Slow CKD

Scientists identify a glycolysis-serine axis controlled by PGK1 that governs podocyte aging, offering a new therapeutic target for chronic kidney disease.

Research Paper
May 25, 2026 0
Smart Hydrogel Targets Osteoarthritis by Restoring Mitochondrial Health in Joints
Longevity & Aging

Smart Hydrogel Targets Osteoarthritis by Restoring Mitochondrial Health in Joints

A peptide-loaded nanocomposite hydrogel disrupts the oxidation-inflammation-aging cycle driving osteoarthritis, protecting cartilage in rat models.

Research Paper
May 25, 2026 0
Boosting Cellular NADPH in Blood Vessel Cells Slows Vascular Aging
Longevity & Aging

Boosting Cellular NADPH in Blood Vessel Cells Slows Vascular Aging

Scientists discover that raising cytosolic NADPH in endothelial cells—via G6PD or folic acid—reverses hallmarks of vascular aging in mice.

Research Paper
May 25, 2026 0
Cardiac CT Scans Offer Powerful Noninvasive Tool for Heart Disease Risk
Longevity & Aging

Cardiac CT Scans Offer Powerful Noninvasive Tool for Heart Disease Risk

Cardiac computed tomography provides fast, cost-effective coronary artery disease assessment using calcium scoring and 3D imaging without invasive procedures.

Research Paper
May 25, 2026 0
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