Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,781 articles
Researchers propose that cells losing their identity and turning mesenchymal is the common thread linking all known hallmarks of aging.
A fractional laser shifted epigenetic markers at 83.9% of aging-linked DNA sites, with visible improvements lasting six months.
Over 3,000 carriers of the top Alzheimer's risk gene will track lifestyle and cognition for years in a landmark real-world study.
REP-0003 targets toxic intracellular cholesterol in artery walls — a rare disease breakthrough with wide cardiovascular aging implications.
A new review identifies PRMT enzymes as master regulators linking mitochondrial stress to sarcopenia and neuromuscular decline.
Researchers mapped the molecular architecture of aging to identify existing drugs that could be repurposed to extend healthy lifespan.
A landmark review identifies 16 objective measures for cancer-related fatigue, moving beyond subjective scales to real physiological data.
A 50-expert international consortium releases updated VasCog-2-WSO criteria, modernizing diagnosis of vascular cognitive impairment for the first time in over a decade.
A natural flavonoid protected middle-aged rats from obesity-driven muscle loss via anabolic signaling, even as it failed to prevent obesity itself.
New review maps ovarian aging cell-by-cell, uncovering mechanisms behind fertility loss and systemic disease risks from estrogen decline.
The European Society of Endocrinology issues comprehensive 2025 clinical guidelines for managing menopause, perimenopause, and premature ovarian insufficiency.
A 34-country study of 18,701 people finds environmental and social exposures accelerate brain aging more than Alzheimer's or dementia diagnoses.
