Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
621 articles
Comprehensive review compares natural compounds, synthetic drugs, and exercise for combating age-related bone loss, muscle weakness, and joint degeneration.
First clinical trial of NAD+ precursor in Werner syndrome patients shows improved arterial stiffness and reduced skin ulcers with no serious side effects.
Comprehensive review finds limited human data supporting off-label rapamycin use for healthy aging despite strong animal studies.
Environmental factors in lab media can completely block metformin's lifespan benefits, while phenformin remains effective.
Large NHANES study reveals pesticide exposure speeds up cellular aging and shortens telomeres through inflammatory pathways.
Large UK study reveals malnutrition increases AMD risk through metabolic changes that damage retinal photoreceptors in middle-aged adults.
New synthetic chemistry approach enables modular assembly of three-dimensional small molecules for drug discovery.
New molecular AI system combines atomic-scale data to accelerate discovery of longevity-enhancing compounds and therapies.
Scientists propose space environments as unique models for studying accelerated aging mechanisms and potential interventions.
Bryan Johnson discusses a significant development in his anti-aging Blueprint protocol journey.
Analysis reveals gap in podcast coverage of cellular senescence despite growing research interest in this aging mechanism.
Natural compounds like quercetin eliminate harmful senescent cells in the uterus, improving decidualization and reducing migration linked to endometriosis.
