Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1273 articles
Repair Biotechnologies' REP-0004 uses mRNA-lipid nanoparticles to clear toxic free cholesterol from the liver, reversing plaque and liver disease.
The submitted press release could not be verified as a recent NIH publication. Content could not be summarized.
WashU Medicine's Long Life Family Study renewal uses long-read sequencing to decode why some families consistently escape age-related disease.
WashU Medicine's Long Life Family Study gets a major boost, using long-read sequencing to find why some families live exceptionally long lives.
A landmark review reveals why aging immune systems lose the ability to clear senescent cells — and how new therapies could restore this critical defense.
A landmark NIH-funded consortium is building the first reference atlas of somatic mutations across healthy human tissues to decode aging and disease.
New research shows taurine suppresses p53-driven senescence in pancreatic β-cells, offering a potential strategy to preserve insulin secretion with age.
A novel SQSTM1-mediated selective autophagy pathway degrades p16 and p21, reducing cellular senescence in degenerative mitral valve disease.
A 2025 review reveals how two sulfur-based amino acids act as master regulators of cellular redox balance and age-related decline.
A new study shows ferroptosis drives cellular senescence, and blocking it with ferrostatin-1 extends lifespan and healthspan in worms and aging mice.
GH drops sharply as we age, mimicking deficiency states — yet boosting it in older adults shows mixed results and real risks.
A longitudinal study of 54 adults finds COVID-19 infection significantly accelerates biological aging across multiple epigenetic clocks.
