Longevity & Aging
Key Enzyme TOP3A Found to Control Cancer's Telomere Survival Trick
TOP3A topoisomerase is essential for ALT, a telomere-maintenance pathway used by 10–15% of cancers, opening new therapeutic targets.
Research Paper
May 23, 2026 0
Topic
Reversing Aging
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,811 articles
Longevity & Aging
Rapamycin Shrinks the Thymus Then Drives It to Rebound Beyond Baseline
Short-term rapamycin causes temporary thymic involution, then triggers regeneration exceeding baseline — hinting at immune rejuvenation as a longevity mechanism.
Research Paper
May 23, 2026 0
Longevity & Aging
How Your Body's Internal Sensing System Shapes the Way You Age
A new review links interoception — the body's ability to sense internal states — directly to aging mechanisms and homeostatic decline.
Research Paper
May 23, 2026 0
Longevity & Aging
Scientists Identify Four Stable Immune Personality Types in Healthy Adults
A 2-year study of 100 healthy adults reveals four distinct, stable immunotypes shaped by innate immune activity—not just age, sex, or CMV status.
Research Paper
May 23, 2026 0
Longevity & Aging
Lipoic Acid Rejuvenates Aging Intestinal Stem Cells Through Paneth Cell Signaling
α-Lipoic acid declines in aged human intestines and supplementation reverses stem cell aging via Paneth cell mTOR inhibition.
Research Paper
May 23, 2026 0
Longevity & Aging
Scientists Crack How mTORC2 Selectively Activates Akt in a Longevity Pathway
A cryo-EM structural study reveals mTORC2 recognizes Akt's 3D protein fold—not just its local sequence—to achieve remarkable substrate selectivity.
Research Paper
May 23, 2026 0
Longevity & Aging
How Cells Repair Their Recycling Centers and Why It Matters for Aging
A landmark review reveals how lysosomal membrane damage triggers repair, death, or renewal — with major implications for aging and disease.
Research Paper
May 23, 2026 0
Longevity & Aging
Premium
Your Cells Have a Growth Switch — Here's Why That Matters for Aging
Discover how a tiny molecular switch inside your cells controls growth, energy use, and how fast you age — and what you can do to keep it in balance.
TutorialBeginner
May 23, 2026 0
Longevity & Aging
Normal B12 Levels May Still Leave Your Brain Vulnerable to Hidden Damage
UCSF researchers find older adults with 'normal' B12 still show cognitive slowing and brain white matter damage.
Press Release
May 23, 2026 0
Longevity & Aging
Key Membrane Lipid Decline Drives Mitochondrial Aging in Worms and Possibly Humans
Scientists find phosphatidylcholine loss fragments mitochondrial networks with age — and supplementing it may help reverse the damage.
Press Release
May 23, 2026 0
Longevity & Aging
Scribe Therapeutics Silences Heart Disease Gene Without Cutting DNA
New CRISPR platform quiets PCSK9 cholesterol gene for 18 months in primates — no permanent DNA edits required.
Press Release
May 23, 2026 0
Longevity & Aging
Oligomerix Completes Phase 1a Trial of Oral Tau-Targeting Alzheimer's Pill
New York biotech reports a favorable safety profile for OLX-07010, an oral drug designed to stop toxic tau protein clumping in the brain.
Press Release
May 23, 2026 0