Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,811 articles
Dihydromyricetin, found in vine tea, acts as a dual senotherapeutic—suppressing SASP in fibroblasts and eliminating senescent microglia in Alzheimer's mice.
The FDA is seeking public input on repurposing approved drugs for new uses, targeting metabolic, neurodegenerative, and rare diseases.
A large retrospective study finds older men with ED face 2x higher sedative abuse risk and 50%+ greater opioid and cocaine risk.
Repair Biotechnologies' REP-0004 uses mRNA-lipid nanoparticles to clear toxic free cholesterol from the liver, reversing plaque and liver disease.
The submitted press release could not be verified as a recent NIH publication. Content could not be summarized.
WashU Medicine's Long Life Family Study renewal uses long-read sequencing to decode why some families consistently escape age-related disease.
WashU Medicine's Long Life Family Study gets a major boost, using long-read sequencing to find why some families live exceptionally long lives.
A landmark review reveals why aging immune systems lose the ability to clear senescent cells — and how new therapies could restore this critical defense.
A landmark NIH-funded consortium is building the first reference atlas of somatic mutations across healthy human tissues to decode aging and disease.
New research shows taurine suppresses p53-driven senescence in pancreatic β-cells, offering a potential strategy to preserve insulin secretion with age.
A novel SQSTM1-mediated selective autophagy pathway degrades p16 and p21, reducing cellular senescence in degenerative mitral valve disease.
A 2025 review reveals how two sulfur-based amino acids act as master regulators of cellular redox balance and age-related decline.
