Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
A major meta-analysis reveals widespread underdiagnosis of Lewy body dementia, the second most common degenerative dementia after Alzheimer's.
A 43-year study of 131,000+ adults found moderate caffeine intake cuts dementia risk by 35% — but more isn't better.
COYA 302 combines low-dose IL-2 and CTLA-4 Ig to boost regulatory T cells and curb ALS-driving inflammation, now on an expedited FDA path.
WHOOP is adding in-app telehealth this summer, letting clinicians analyze your continuous biometric data alongside medical records and lab work.
A comprehensive review maps every major in vitro aging model—from Hayflick's fibroblasts to iPSCs—and the interventions that reverse cellular aging.
The International Society of Sports Nutrition's comprehensive 2025 review affirms HMB's safety and multi-faceted benefits for muscle, performance, and aging.
Ergothioneine, found in edible fungi, activates SIRT1/Nrf2 signaling in hair follicle cells to reduce oxidative damage and reverse aging-related hair loss.
A Mendelian randomization study identifies GPX1 as a shared druggable target for frailty and hypertension, mediated by glycine and carnitine pathways.
A landmark review unifies brain waste clearance and immune surveillance, revealing how CSF flow, sleep, and meningeal immunity protect against neurodegeneration.
Intermittent fisetin dosing in old mice reduced frailty and boosted grip strength, matching results from genetic and synthetic senolytic approaches.
Procyanidin C1, a natural polyphenol, reduces aging-related skin scarring by targeting EGFR and shutting down fibrosis signaling pathways.
A comprehensive review reveals how one gut bacterium influences metabolism, immunity, cancer response, and longevity across multiple disease states.
