Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
A large Chinese cohort study finds that higher psychological frailty scores strongly and linearly predict incident stroke, independent of traditional risk factors.
A new Gompertz-based algorithm converts standard clinical biomarkers into a biological age estimate that predicts mortality, frailty, and chronic disease risk.
A new composite index blending lipid dysregulation and frailty predicts CVD, stroke, and heart disease with striking accuracy over 9 years.
A 7-year Chinese cohort study finds that higher frailty scores and accelerated biological aging independently and jointly predict new COPD diagnoses.
Scientists trace age-related memory loss to gut bacteria that inflame nerves, silencing the gut-brain axis and crippling hippocampal memory formation.
A gut-derived metabolite called phenylacetic acid rises with age and causes blood vessel cells to senesce, linking the microbiome to cardiovascular aging.
Dysfunctional meningeal lymphatics disrupt cortical E/I balance through microglia-driven IL-6 signaling — and restoring them reverses aging-related cognitive decline.
Researchers critically reassess 13 years of glymphatic research and find no confirmed causal link to Alzheimer's disease in humans yet.
A landmark review identifies wearable and digital biomarkers of aging across eight body systems, evaluating their validity, cost, and clinical utility.
A Johns Hopkins review reveals how AI-driven wearables, sensors, and smart devices are transforming senior care through continuous health monitoring.
A new single-cell study reveals SLC35F1 loss in cochlear hair cells drives primate hearing decline — and metformin may slow it.
A 2025 review reveals metformin's promising dermatological applications—from acne and psoriasis to wound healing and anti-aging effects.
