Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
A large retrospective study finds GLP-1 receptor agonists reduce risk of macular degeneration and glaucoma by up to 32% compared to other medications.
University of Rochester scientists moved a longevity gene from naked mole rats into mice, boosting lifespan 4.4% and cutting cancer risk.
A detailed review of how genomic selection, wearable sensors, and multi-trait breeding are reshaping dairy cattle for health, longevity, and sustainability.
A major 2025 review reveals how dietary flavonoids neutralize free radicals and dampen inflammation driving cancer, neurodegeneration, and heart disease.
Deleting HSP60 in astrocytes causes mitochondrial failure and cellular senescence, disrupting neuroregeneration via the S1P/truncated-BDNF pathway.
Loss of chitinase-like 4 disrupts olfactory stem cell cycling, kills a unique neuron subtype, and triggers brain-like inflammation in the nose.
New review reveals how simultaneous bone and muscle loss dramatically worsens outcomes across heart, kidney, liver, and lung diseases.
A scarlet beebalm extract rich in the flavonoid didymin improved telomere length and stabilized epigenetic age in a double-blind clinical trial.
Researchers identify four senescence-enriched vascular cell clusters in atherosclerotic mouse aortas and derive a conserved transcriptomic signature including Spp1, Ctsb, and Tnfrsf11b.
Traditional kidney-tonifying formulas ZGP and YGP extend C. elegans lifespan via kaempferol-driven mitophagy, revealing a molecular mechanism behind TCM anti-aging effects.
Researchers built MoveIt! Age, a wearable-only biological age clock using daily step data that outperforms blood tests in predicting frailty and mortality.
A new Nature Communications study reveals NONO, SFPQ, and PSPC1 proteins guide telomerase from Cajal bodies to telomeres, with their loss causing progressive telomere shortening.
