Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
A comprehensive review of in vitro assays for inducing cellular senescence and screening senolytic drugs, highlighting key challenges in clinical translation.
Fucoidan, dasatinib+quercetin, and MitoQ each counteract hyperoxia-driven cellular senescence in fetal airway cells via distinct mechanisms.
A systematic review reveals quercetin's multi-pathway mechanisms in combating ovarian aging, PCOS, premature ovarian insufficiency, and chemo-induced damage.
A sweeping 2025 review maps how the plant compound quercetin combats cardiovascular disease, dementia, osteoporosis, and more at the molecular level.
New research shows psilocybin boosts survival in aged mice by 30% and extends human cell lifespan up to 57% in lab studies.
Researchers built an aging clock from wrist PPG wearable data of 213,000+ people, linking biological age gap to heart disease, diabetes, and behavior.
A single dose of TERT circular RNA reverses hallmarks of vascular senescence more powerfully and durably than standard mRNA in progeria endothelial cells.
New research shows that reduced FTO expression drives granulosa cell senescence, cutting fertility-related hormone output and accelerating ovarian aging.
A landmark 2025 review maps the molecular and cellular mechanisms driving immune aging, linking inflammaging to cancer, neurodegeneration, and infection.
A 2026 review evaluates how two common dietary flavonoids target senescent cells, potentially slowing aging and age-related disease.
A new study pinpoints chemotherapy-induced senescent bone marrow cells as the culprit behind bone loss, and shows senolytics can prevent it.
Tiny vesicles extracted from plants show remarkable potential to repair tissues and slow aging with high safety and low cost.
